Director of Oligonucleotide Innovation

2 weeks ago


Rajahmundry, Andhra Pradesh, India beBeeOligosynthesis Full time ₹ 1,20,00,000 - ₹ 2,00,00,000
Scientific Officer - Oligo Synthesis

Expertise in oligo synthesis and analysis is required to join a pioneering team developing groundbreaking diagnostics and therapies. As a PhD-level Scientific Officer, lead the design, development, and implementation of precision-driven solutions in genomics and beyond.

About the Role:

Deliver innovative results by running and troubleshooting automated solid-phase synthesis, scaling synthesis to mmol level, purifying and characterizing oligos, maintaining lab instrumentation, and driving cross-functional method development and QC initiatives.

  • Automated Solid-Phase Synthesis: Troubleshoot detritylation–oxidation cycles.
  • Scaling Synthesis: Achieve coupling efficiency >99% at mmol level.
  • Purification and Characterization: Utilize HPLC, PAGE, CE for purification and LC-MS, UV-Vis, MS for characterization.
  • Maintenance: Maintain lab instrumentation, inventory, safety, and SOPs.
  • Cross-Functional Method Development: Drive initiatives with multiple teams.
Qualifications:
  • Ph.D. + 2–5 yrs experience in oligo synthesis and analysis.
  • Strong foundation in phosphoramidite chemistry, purification, and analytics.
  • Bonus: Experience with modified or therapeutic oligos, digital PCR/BEAMing.


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