Lead Medicinal Chemist

2 weeks ago

Pune, Maharashtra, India beBeeChemist Full time ₹ 15,00,000 - ₹ 25,00,000
Job Title

A Research Scientist is required to work in a biotech R&D organization dedicated to discovering and developing novel therapeutics, diagnostics, and devices for diseases with a high socio-economic impact.

As part of our team, you will be responsible for designing and executing synthetic routes to prepare small molecules for drug discovery programmes. You will also track SAR and optimize potency, selectivity, and properties of small molecules for research programs.

The ideal candidate will have a strong background in organic chemistry, medicinal chemistry or a closely related field. A PhD in organic chemistry / medicinal chemistry is preferred, but not essential.

Key Responsibilities:

  • Design and execute synthetic routes to prepare small molecules for drug discovery programmes
  • Track SAR and optimizing potency, selectivity, and properties of small molecules for research programs
  • Perform purification and structural characterization of compounds
  • Troubleshoot synthetic problems and optimize reaction conditions
  • Provide mentorship and guidance to junior colleagues
  • Maintain accurate lab records and contribute to technical reports
  • Collaborate with analytical teams as needed
  • Provide input on intellectual property activities

Requirements:

  • Skilled in multistep organic synthesis, reaction optimization, and compound isolation
  • Proficient in chromatography (TLC, column, flash), spectroscopic analysis (NMR, LC-MS, HPLC), and purification techniques (recrystallization, precipitation, others)
  • High level of creativity and productivity with strong synthetic chemistry problem solving skills
  • Demonstrated excellence in organic synthesis, conversant with the current literature
  • Effective oral and scientific/technical writing communication skills
  • Ability to work independently and collaboratively within a team
  • Commitment to lab safety and adherence to safety protocols
  • Familiarity with reaction databases (e.g., Reaxys, SciFinder)
  • Proficiency using MS Office applications

Benefits:

  • Competitive salary package
  • Opportunity to work on exciting projects
  • Collaborative and dynamic work environment

How to Apply:

Interested candidates should submit their CV and a cover letter outlining their experience and qualifications. We look forward to hearing from you

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