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Invitro-BA scientist

1 month ago

Bengaluru, India Syngene Full time

JOB DESCRIPTION

Job Title: Invitro ADME Bioanalyst

Job Location: Bangalore

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines

Hold self and their teams accountable for the achievement of safety goals Govern and Review safety metrics from time to time

Core Purpose of the Role:

Bioanalytical scientist familiar in handling HPLC and support ADME screening assays: Formulations analysis, solubility studies, stability studies, ectc. and understanding of LCMS in line with business needs.

Role Accountabilities

Optimization of test compounds and to develop high throughput, fit for purpose HPLC-UV methods to support ADME samples analysis: Formulations analysis, solubility studies, stability studies, ectc. Perform analysis of samples generated for the screening of compounds for ADME assays and Processing of different matrices/formulation samples of PK studies Good written and oral communication skills interacting with internal stakeholders Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system Preparation of protocols, reports and templates for responsible activities Instrument maintenance, calibration and maintaining documentation as per regulatory requirements and company policy Adhering to safety and quality policies laid by organization

Leadership Capabilities: NA

Syngene Values

All employees will consistently demonstrate alignment with our core values

 Excellence  Integrity  Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)

Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities. Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance. Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Specific requirements for this role

Experience: Minimum 2 to 4 years of relevant industrial experience Demonstrated Capability: Hands-on experience in handling of LC-MS/MS systems is mandatory and experience on HRMS is advantageous Expertise in column selection, mobile phase selection, solvent preparations and sample processing techniques such as protein precipitation, liquid-liquid extraction and solid phase extraction Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assay samples analysis. Basic knowledge on Large molecule and Peptides analysis using LCMS/HRMS Should assist/deliver the scientific presentation in departmental journal club and write official Project reports Should be equipped with quality policies related to data management and data integrity Education: M. Pharm in Pharmaceutical sciences/ Relevant master’s degree in pharmaceutical sciences or instrumentation

Skills and Capabilities:

Good communication skills Strong problem-solving and handling skills Team Player Ability to learn/implement new assay in ADME and Analytical Quality compliance skills

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