
Research Associate
18 hours ago
Key Responsibilities
- Design and execute peptide synthesis processes (SPPS / solution phase / hybrid approaches)
for API development.
- Optimize reaction conditions, resin selection, coupling strategies, and cleavage protocols to
achieve high yield, purity and productivity.
- Develop and validate purification processes (prep HPLC/UPLC, crystallization, lyophilization).
- Conduct analytical characterization of intermediates and final peptide APIs using HPLC, LC-
MS, NMR, FT-IR and other relevant techniques.
- Support process scale-up from lab to pilot/plant scale, ensuring reproducibility and
regulatory compliance.
- Prepare process development reports, technology transfer documents, and regulatory
submissions (CMC sections).
- Ensure adherence to GMP, ICH, USFDA, EMA, and other regulatory guidelines.
- Collaborate closely with Process Engineering, Production, QA, QC, and Regulatory Affairs
for successful API development.
- Troubleshoot technical challenges during development and scale-up.
Qualifications
- Education: M.Sc / M.Tech / Ph.D. in Organic Chemistry, Peptide Chemistry, Medicinal
Chemistry, Biochemistry, or related field.
Experience:
- 1 to 3 years (Research Associate Entry level)
- 3 to 6 years (Scientist Mid-level)
6+ years (Senior Scientist Lead level)
Strong hands-on experience in peptide API process development, purification, and scale-
up.
- Knowledge of regulatory expectations for APIs and CMC documentation preferred.
Desired Skills
- Expertise in solid-phase and solution-phase peptide synthesis.
- Experience in process optimization, scale-up, and technology transfer.
- Familiarity with ICH Q7, GMP guidelines, and regulatory frameworks.
- Strong analytical and troubleshooting skills.
- Proficiency with analytical instruments (HPLC, LC-MS, NMR).
- Excellent communication, documentation, and teamwork skills.
- Innovative mindset to stay updated on the latest trends in peptide chemistry for creating IP
wealth.
Key Competencies
- Scientific rigor and attention to detail.
- Ability to manage multiple projects and timelines.
- Strong problem-solving and process improvement mindset.
- Commitment to safety, compliance, and quality.
Interested Candidates can share their resumes on
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