Research Associate

5 days ago

Gurgaon, Haryana, India Walter Bushnell Full time ₹ 8,00,000 - ₹ 12,00,000 per year

Key Responsibilities

  • Design and execute peptide synthesis processes (SPPS / solution phase / hybrid approaches)

for API development.

  • Optimize reaction conditions, resin selection, coupling strategies, and cleavage protocols to

achieve high yield, purity and productivity.

  • Develop and validate purification processes (prep HPLC/UPLC, crystallization, lyophilization).
  • Conduct analytical characterization of intermediates and final peptide APIs using HPLC, LC-

MS, NMR, FT-IR and other relevant techniques.

  • Support process scale-up from lab to pilot/plant scale, ensuring reproducibility and

regulatory compliance.

  • Prepare process development reports, technology transfer documents, and regulatory

submissions (CMC sections).

  • Ensure adherence to GMP, ICH, USFDA, EMA, and other regulatory guidelines.
  • Collaborate closely with Process Engineering, Production, QA, QC, and Regulatory Affairs

for successful API development.

  • Troubleshoot technical challenges during development and scale-up.

Qualifications

  • Education: M.Sc / M.Tech / Ph.D. in Organic Chemistry, Peptide Chemistry, Medicinal

Chemistry, Biochemistry, or related field.

Experience:

  • 1 to 3 years (Research Associate Entry level)
  • 3 to 6 years (Scientist Mid-level)

  • 6+ years (Senior Scientist Lead level)

  • Strong hands-on experience in peptide API process development, purification, and scale-

up.

  • Knowledge of regulatory expectations for APIs and CMC documentation preferred.

Desired Skills

  • Expertise in solid-phase and solution-phase peptide synthesis.
  • Experience in process optimization, scale-up, and technology transfer.
  • Familiarity with ICH Q7, GMP guidelines, and regulatory frameworks.
  • Strong analytical and troubleshooting skills.
  • Proficiency with analytical instruments (HPLC, LC-MS, NMR).
  • Excellent communication, documentation, and teamwork skills.
  • Innovative mindset to stay updated on the latest trends in peptide chemistry for creating IP

wealth.

Key Competencies

  • Scientific rigor and attention to detail.
  • Ability to manage multiple projects and timelines.
  • Strong problem-solving and process improvement mindset.
  • Commitment to safety, compliance, and quality.

Interested Candidates can share their resumes on

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