
Senior Biopharmaceutical Research Scientist
7 days ago
Job Overview:
This role is focused on leading the design and execution of DMPK studies to support antibody-drug conjugate (ADC) and monoclonal antibody (mAb) programs, from discovery through IND-enabling stages.
Key Responsibilities:
- Expertly design and execute complex DMPK studies to support ADC and mAb programs, ensuring timely delivery of high-quality data.
- Develop and apply innovative techniques for function-based identification and selection of ADC and mAb lead candidates, with a strong focus on DMPK profiling.
- Collaborate closely with cross-functional teams to address ADC-related challenges and deliver integrated solutions from target validation to IND submission.
- Author and review SOPs, study protocols, reports, and regulatory documentation to support both GLP and non-GLP studies.
- Stay up-to-date with the latest advancements in DMPK principles, including PK/PD, toxicology, and translational sciences.
Required Skills and Qualifications:
- Extensive experience in quantification of biologics using LC-MS/MS, MSD, and ELISA platforms.
- Proficient in advanced bioinformatics tools such as BioPharma Finder, MaxQuant, Spectronaut, and other relevant analytical software.
- Strong foundational knowledge of DMPK principles, including PK/PD, toxicology, and translational sciences.
- Excellent communication, innovation, and team leadership skills.
Benefits:
- Contribute to the development of novel ADC and mAb therapies that transform patient lives.
- Work collaboratively in a dynamic, interdisciplinary environment.
- Participate in professional development opportunities to stay current with industry trends.
Competencies:
- Antibody, ADC characterization
- Communication skills
- Excel software skills
- Interpersonal skills
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