
Research Scientist
2 days ago
The Senior Research Associate will be a key member of our research team, responsible for conducting preclinical laboratory experiments to support annual goals and objectives for Translational Medicine. This role requires strong technical skills in cell culture, gene expression methods, protein analyses, and in vivo pharmacology models. Additionally, excellent verbal and written communication skills are essential for this position.
Key Responsibilities:
- Conduct preclinical laboratory experiments on late-stage compounds to support annual goals and objectives for Translational Medicine
- Deliver data in support of translational strategies including biomarkers, patient selection hypotheses, dose and schedule, combination strategies, resistance mechanisms, and differentiation
- Interface with TM scientists across departments to ensure seamless flow of information for assets which are entering the remit of translational medicine
- Assist in designing experiments and delivering data for collaborative projects along with TM scientists
Required Skills and Qualifications:
- Masters with at least 2 years of relevant work experience across immunology, oncology, heme-oncology focus areas
- Industry experience is a plus
- Excellent technical skills in cell culture, primary cell isolation, cell transfection, and single-cell cloning, including siRNA, CRISPR, TALEN, or HDR workflows
- Gene expression methods including qRT-PCR and/or familiarity with RNA sequencing, epigenomic methods including methylation analysis, ChIP
- Protein analyses and immunoassays, and cell phenotyping analysis, e.g., ELISA, MSD, Luminex, TSA, CBA, flow cytometry
- Design, setup, and execution of autoimmune, solid tumor oncology, or heme-oncology in vivo pharmacology models
- Excellent verbal and written communication skills
- Familiarity with standard or relevant software platforms, and scientific qualities are expected
- Competence in analysis and solving of problems, keeping track of overall goals, and maintaining a good understanding of the methodological basis and biological significance of assays performed
Benefits:
- A self-starter who is able to become technically proficient in a diverse set of techniques and assays with a focus on quality and speed
- Will meticulously follow internal SOPs
- Good basic lab skills required, pipetting, balances, etc.
- Highly detailed and meticulous, high standards of data entering and QC
- Must be highly adaptive to changing timelines and goals
- Must be comfortable taking on complex tasks with minimal direct supervision
- An excellent multitasker with an ability to be level-headed in a fast-paced lab setting
- Team-oriented and comfortable working in a highly dynamic matrix environment across multiple locations
Equal Opportunity Employer:
Syngene is an equal opportunity employer and provides reasonable accommodations for qualified individuals with disabilities.
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