
Synthetic Data Engineer
1 week ago
Role Overview
We are seeking an experienced Data Scientist to lead the design and implementation of intelligent frameworks for synthetic and automated test data generation.
Key Responsibilities
- Synthetic Test Data Automation
- Develop cutting-edge algorithms to generate realistic clinical and operational datasets.
- Produce standardized datasets (SDTM, ADaM) for seamless integration with data transformation, analysis, and reporting workflows.
- Simulate complex datasets (adverse events, labs, demographics, drug exposure) with variability and referential integrity.
- Design connectors for Define-XML, Pinnacle21 validation, and statistical programming workflows.
- AI/ML in Data Generation
- Apply generative AI (LLMs, GANs, diffusion models) to model intricate clinical scenarios.
- Create synthetic patient journeys across EDC, eCOA, CTMS, LIMS, and PV systems.
- Utilize AI-driven automation to simulate rare or complex cases for stress and edge-case testing.
- Compliance & Data Governance
- Ensure adherence to regulatory standards (GxP, 21 CFR Part 11, HIPAA, GDPR).
- Implement robust anonymization/obfuscation techniques while maintaining clinical and statistical fidelity.
- Develop validation protocols and documentation for audit and inspection readiness.
- Collaboration & Integration
- Work closely with Clinical Data Management, Biostatistics, Pharmacovigilance, and Compliance teams to gather requirements.
- Embed test data generation into CI/CD pipelines, trial simulations, and automated validation environments.
- Partner with subject matter experts to validate AI-generated datasets for regulatory acceptability.
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