Team Lead: Invitro ADME

Job Description

Date: 22 Jul 2025

Location:

Bangalore, KA, IN, 560099

Custom Field 1: Discovery Services

Job Title: Team Lead - ADME Scientist

Job Location: Bangalore/Hyderabad

About Syngene

Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit.

Mandatory expectation for all roles as per Syngene safety guidelines

- Overall adherence to safe practices and procedures of oneself and the teams aligned.
- Contributing to development of procedures, practices and systems that ensures safe operations and compliance to companys integrity & quality standards.
- Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
- Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
- Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self.
- Compliance to Syngene s quality standards at all times.
- Hold self and their teams accountable for the achievement of safety goals
- Govern and Review safety metrics from time to time

Core Purpose Of The Role

- Conduct in vitro ADME experiments, mentoring junior team members and adapt to dynamic changes in the day-day activities.
- Interact with cross functional scientific teams and external collaborators and remain as a subject matter expert in the field of ADME sciences
- Communication with the client for any queries and trouble shooting
- Identification of new technologies to support highly demanding ADME sciences
- Responsible for generation of high-quality data, reviewing and uploading data into data bases with additional QC checks
- Develop capabilities for leading collaborative integrated drug-drug programs
- Contemporaneous recording of lab activities and experiments performed, practices high level of house keeping
- Adhere to all safety rules and maintains safe workplace
- Identification or establishment of need for any invitro ADME related assays

Role Accountabilities

- Extensive experience in planning in-vitro ADME assays.
- Design and execute In vitro ADME assays of different types, viz., non-cell based assays. (Physicochemical assays such as solubility, Log-D, Log P), Protein binding assays and PAMPA.
- Hands on experience on Sirius T3 instrument.
- Integrate the Physicochemical assays, PAMPA and protein binding data in drug discovery paradigm for informed decision making the progression of molecules.
- Experience in managing a team of 5 10 people is absolutely.
- Seamless coordination with direct reportee (4-5) and supervisor to deliver the study results within the acceptable or agreed time- lines.
- Setting up KRA / KPI for the team members and monitoring their performance.
- Seamless coordination with BA-DMPK group to design in-vitro ADME studies.
- Automation of In vitro ADME assays.
- Preparation of SOPs and EOPs.
- Reporting of executed studies without any noncompliance.
- Reporting of study results clearly in the cross functional scientific meetings.
- Ensuring that there are no safety non-compliances in areas that my team operates in.
- Ensuring adherence to all Syngene policies related to data integrity by all members of the team including self
- Ensuring all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
- Reporting incidents (or near-misses) and learnings from those incidents to avoid recurrence.
- Compliance to Syngene s quality standards at all times and ensuring the same by the team members.
- Hold self and their teams accountable for the achievement of safety goals
- Govern and Review safety metrics from time to time

Syngene Values: All employees will consistently demonstrate alignment with our core values

- Excellence
- Integrity
- Professionalism

Accountabilities As a Syngene Leader

- Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
- Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
- Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Experience

- A Ph.D. in pharmaceutical sciences or biological science. 3-6 years experience/Ph.D or M Pharm. in pharmaceutical sciences with fifteen or more years of Industrial experience in DMPK/ADME research.

Educational Qualification

- A Ph.D. or Postdoctoral experience in pharmaceutical or biological sciences or M Pharm. in any pharmaceutical science.

Technical/functional Skills

- Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assays
- Sound knowledge in troubleshooting the cell culture assays
- Good, demonstrated knowledge in software such as Microsoft excel and Graph pad prism
- Demonstrated cross functional leadership capabilities
- Experience with automation is desirable

Behavioral Skills

- Demonstrate ability to be a team player.
- Commitment to deliver the study reports within the agreed timelines
- Adaptability to changes in the dynamic lab environment
- Communicate confidently with colleagues and collaborators in the meetings and presentation of study reports and evidence of publications in the PEER reviewed Journals

Equal Opportunity Employer

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

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