Principal IS Architect

Principal IS Architect - Veeva Vault Platform

Career CategoryInformation Systems Job Description Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do

Let's do this. Let's change the world. In this vital role you will set platform-wide architectural guardrails, ensure every Vault shares a scalable, compliant foundation, and translate complex business needs into elegant, reusable designs that accelerate R&D, Quality, Safety, Medical and Commercial outcomes.

Roles & Responsibilities:

• Define and maintain the enterprise Vault reference architecture—objects, lifecycles, security, integrations, data models.
• Lead high-impact design reviews for new Vault modules, major enhancements and integrations, ensuring consistency, performance and reuse.
• Partner with data governance and integration leads to deliver a canonical data model and API strategy that supports end-to-end processes.
• Provide expert guidance on validation-ready design, risk scoring and change control to safeguard GxP compliance.
• Mentor configuration engineers and domain solution architects; publish standards, patterns and best-practice blueprints.
• Evaluate Veeva road-map features (e.g., new APIs, AI services) and advise on adoption strategy and enterprise impact.
• Act as a customer concern point for complex production issues, performance tuning and architectural deviations.
• Maintain comprehensive documentation of the platform architecture, including principles, standards, user guides, and model
• Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
• Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
• Establish and enforce data standards, governance policies, and best practices
• Provide domain expertise in Veeva Vault to the team, offering guidance on architecture, solution design, and implementation challenges.
• Provide hands-on technical leadership in resolving complex technical issues and ensuring smooth deployment and system integration

What we expect of you

We are all different, yet we all use our unique contributions to serve patients.

Basic Qualifications:

• Doctorate degree / Master's degree / Bachelor's degree and 12 to 17 years Business, Engineering, IT or related field

Preferred Qualifications:

Functional Skills:

Must-Have Skills:

• Strong understanding of architecting and deployment strategies for integrations to Veeva Vault Platforms/Products.
• Expertise in system integration, including APIs, middleware tools, and data migration between Vault and other systems.
• Deep expertise in Vault object/lifecycle design, security model and integration patterns.
• Proven ability to create cross-domain, reusable architectures that scale across multiple Vaults and business functions.
• Strong grasp of CSV and regulatory requirements; able to embed compliance into design artifacts.
• Excellent stakeholder-facing communication—able to explain architectural trade-offs to executives and developers alike.
• Strong knowledge of Data Lake technologies like Databricks, etc.
• Experience in Mulesoft and Python script development
• Experience with system integration and IT infrastructure
• Experience with data, change, and technology governance processes on the platform level
• Experience working in agile methodology, including Product Teams and Product Development models
• Proficiency in designing scalable, secure, and cost-effective solutions.
• Have partner and team management skills
• Can lead and guide multiple teams to meet business needs and goals

Good-to-Have Skills:

• Experience with adjacent enterprise platforms (Salesforce, SAP, Boomi/Mule, Snowflake) and API management.
• TOGAF, SAFe Architect, or similar enterprise architecture certification.
• Exposure to data-governance frameworks (IDMP, SPOR, master data).
• Good Knowledge of the Global Pharmaceutical Industry
• Understanding of GxP process
• Strong solution design and problem-solving skills
• Strong understanding of technology, function, or platform
• Experience in developing differentiated and deliverable solutions
• Ability to analyze client requirements and translate them into solutions
• Working late hours

Professional Certifications (please mention if the certification is preferred or mandatory for the role):

• Veeva Vault Platform Administrator (mandatory)
• Scaled Agile Framework (SAFe) for Teams (mandatory)
• Scaled Agile Framework (SAFe) – DevOps Practitioner (preferred)
• ITIL (preferred)

Soft Skills:

• Excellent leadership and team management skills.
• Strong transformation and change management experience.
• Exceptional collaboration and communication skills.
• High degree of initiative and self-motivation.
• Ability to manage multiple priorities successfully.
• Team-oriented with a focus on achieving team goals.
• Strong presentation and public speaking skills.
• Excellent analytical and solving skills
• Strong verbal and written communication skills
• Ability to work effectively with global, virtual teams

Shift Information:

This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements.

Equal opportunity statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided with reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now and make a lasting impact with the Amgen team. . Experience LevelSenior Level

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