MS&T Technical Manager

3 days ago


Mumbai, Maharashtra, India Novartis Full time ₹ 12,00,000 - ₹ 36,00,000 per year
Summary

Lead and manage all Manufacturing Science & Technology activities for the assigned

Contract Manufacturing Organizations (CMOs). This includes providing product stewardship by ensuring the performance of all NVS products are monitored and maintained in a validated state, supporting root cause investigations by providing MS&T intelligence to deviations, technical complaints, OOS & CAPAs, identifying and executing continuous improvement

opportunities.

Acts as the ESO Project Team Lead (PTL) for new product launch at CMO's / technology transfer at CMO's. Assembles and leads a cross-functional team to ensure the successful transfers of manufacturing at CMOs. Ensures appropriate project management to achieve milestones in time, with required quality and in budget by leading the respective technical sub-team and liaising efficiently with related functions.

Supports the MS&T organization by leading ESO-wide initiatives and/or work-streams and representing ESO MS&T in various global networks.

About the Role

General

Job Title

Technical Manager MS&T

Department

External Supply Operations - Manufacturing Science and Technology (MS&T)

Reports to (Job Title)

Functional Lead MS&T – ESO

Key Responsibilities:

Lead and manage all Manufacturing Science & Technology activities for the assigned

Contract Manufacturing Organizations (CMOs). This includes providing product stewardship by ensuring the performance of all NVS products are monitored and maintained in a validated state, supporting root cause investigations by providing MS&T intelligence to deviations, technical complaints, OOS & CAPAs, identifying and executing continuous improvement

opportunities.

Acts as the ESO Project Team Lead (PTL) for new product launch at CMO's / technology transfer at CMO's. Assembles and leads a cross-functional team to ensure the successful transfers of manufacturing at CMOs. Ensures appropriate project management to achieve milestones in time, with required quality and in budget by leading the respective technical sub-team and liaising efficiently with related functions.

Supports the MS&T organization by leading ESO-wide initiatives and/or work-streams and representing ESO MS&T in various global networks.

Major Accountabilities

Product Stewardship

  • As Product Steward, ensure that the products stay in a validated state and their technical

performance/capability is monitored.

  • Major accountabilities include:

  • Assessing impact of manufacturing changes.

  • Providing MS&T intelligence to deviations, investigations, OOE's and OOS's, technical

complaints.

- Defining and tracking technical CAPAs resulting from APR/PQR assessments or

manufacturing variances.

- Providing MS&T intelligence to APR/PQR and delivering the performance capability results,

interpretations and recommended CAPAs;

- Identifying process optimization opportunities and executing them when approved;

- Identifying and leading product manufacturing remediations.

- Establishing and executing product revalidation strategies including approval of QRAs,

validation protocols and reports.

- Establishing and executing continued process verification strategies and annual verification.

- Ensuring maintenance of knowledge for the manufacturing of NVS products.

Product Transfers and New Product Launch

  • Leads a cross functional team for product transfers/launches to 3rd parties (process,

technology, analytics, capacity, resources).

  • Ensures appropriate project management to achieve milestones in time, with required quality

and in budget by leading the respective technical sub-team and liaising efficiently with related

functions.

  • Provides technical expertise together with manufacturing experts.
  • Supports CMO site selection and ensure right technical fit for transfer/launch
  • Defines and monitors technical project scope, timing and progress in collaboration with Giving

Site or TRD

  • Writes Manufacturing Process Transfer Documents (protocol, report).
  • Coordinates feasibility, regulatory and validation batches at site.
  • Initiates monitoring and Continued Process Verification CPV phase.
  • Ensures that all activities are performed to current standards (current Good Manufacturing

Practices cGMP, Health Safety Environment HSE, Regulatory etc.).

  • Supports continuous process and quality improvements.
  • Supports QA to ensure inspection readiness (Pre Approval Inspection PAI).

Essential Requirements:

  • Technical transfer milestones achieved on time and in full, including schedule for registration and launches.
  • Robust manufacturing process at CMO, delivering critical quality attributes.
  • Analytical methods in place, meeting cGMP standards.
  • No critical observations during internal and external GMP inspections and Pre-Approval Inspections (PAI).
  • Adheres to project / Capital Approval Request CAR costs.

  • Recognized as an excellent collaborator and partner by the CMOs, SRTs, QA and others partner functions (R&D)

  • When acting as Product Steward, meet related KPIs:
  • Product is maintained in constant state of validation.
  • Product history is documented and available and current since transfer from development/transfer to CMO to date.
  • Recurring Deviations.
  • Continuously improving CpK – process capability.
  • Degree of standardization of product process
  • OoS, OoE – Out of Specification, Out of Expectation.
  • Customer Complaints.
  • Recalls.
  • Success rate of Health Authorities' inspections.
  • Completeness of Reg CMC dossier
  • Effective CAPA.
  • Continuously improving Yield.
  • Technical reports executed on time and with the right expectations.

Job Dimensions

Number of associates:

None (may have direct reports depending on Division)

Financial responsibility:

(Budget, Cost, Sales, etc.)

Impact on the organization:

Strengthen product/process manufacturing performance, reducing product quality complaints.

Improve Supply Chain performance by increasing process robustness, minimizing recalls, rejected batches and write- offs.

High

Ensures that Novartis products manufactured at CMOs meet stay in a validated state, are trended and optimization potential are implemented.

Ensures Transfers and launches are executed according to

plan

Contribute to ESO Manufacturing financial /business/quality goals.

Minimize rejected batches and write-offs.

Maximize Yield improvements.

Desirable Requirements:

Education:

  • BSc / MSc. / BTech or MTech (Chemistry / Chemical Technology) or equivalent scientific degree.
  • Highly desirable: MSc. or equivalent experience.

Language:

  • Fluent in English

Experience:

  • 10 yrs of experience in a pharmaceutical manufacturing-API/technical environment/Technology transfer and project management.
  • Strong leadership skills with a minimum of 5 years managerial experience
  • Demonstrated technical expertise in manufacturing science and drug development.
  • Project management skills
  • Significant knowledge of industry practices and regulations (e.g. GxP, ISO, ICH / VICH, etc.) across multiple health authorities (e.g. FDA, EMEA, Health Canada, etc.)
  • Statistical knowledge required, Lean/Six Sigma Certification preferred
  • Demonstrated leadership and accomplishments in a global/matrix environment in the pharmaceutical industry
  • Strong project management, interpersonal, cross-cultural, communication, negotiation and problem-solving skills

Novartis Competencies

Leadership Standards

Fundamental

Intermediate

Advanced

Thought Leader

Sets Clear Direction & Aligns Team & Others Around Common Objectives

Energizes The Team

Display Passion For The 3Cs

Exercises Good Judgement & Drives Change For Competitive Advantage

Drives For Superior Results & Has Passion To Win

Builds The Talent Pipeline

Inspires Continuous Improvement & Breakthrough Thinking

Displays Analytical & Conceptual Thinking

Functional Competencies

Functional Competencies

Fundamental

Intermediate

Advanced

Thought Leader

  • Manufacturing process science

  • Manufacturing process technologies

  • Quality Compliance

  • Problem Resolution

  • Project Management

  • Operations

  • Finance

  • IT/Automation

  • HSE

Lominger Competencies

Fundamental

Intermediate

Advanced

Thought Leader

  • Decision Quality

  • Problem Solving

  • Functional/Technical Skills

  • Technical Learning

  • Integrity and Trust

  • Intellectual horsepower

  • Planning

  • Drive for Results

  • Total Work Systems

  • Action Oriented

  • Process Management

  • Strategic Agility

Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us Learn more here:

You'll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook.

Commitment to Diversity and Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here:

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up:

Benefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally:

Division

Operations

Business Unit

Universal Hierarchy Node

Location

India

Site

Mumbai (Head Office)

Company / Legal Entity

IN10 (FCRS = IN010) Novartis Healthcare Private Limited

Functional Area

Technical Operations

Job Type

Full time

Employment Type

Regular

Shift Work

No

Accessibility and accommodation

Novartis is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.



  • Mumbai, Maharashtra, India Novartis Full time

    Job Description Summary Lead and manage all Manufacturing Science & Technology activities for the assigned Contract Manufacturing Organizations (CMOs).This includes providing product stewardship by ensuring the performance of all NVS products are monitored and maintained in a validated state, supporting root cause investigations by providing MS&T...


  • Mumbai, Maharashtra, India Novartis Full time

    Job Description Summary Lead and manage all Manufacturing Science & Technology activities for the assigned Contract Manufacturing Organizations (CMOs).This includes providing product stewardship by ensuring the performance of all NVS products are monitored and maintained in a validated state, supporting root cause investigations by providing MS&T...


  • Mumbai, Maharashtra, India L&T Technology Services Ltd. Full time ₹ 15,00,000 - ₹ 60,00,000 per year

    Head Finishing, L&T RealtyLNT/H-R/1497863RELT-RealtyMumbaiPosted On30 Sep 2025End Date29 Mar 2026Required Experience YearsSkillsKnowledge & Posting LocationFINISHING WORKSMinimum QualificationB.TECH/BEJob DescriptionPosition:Head Finishing, L&T RealtyReporting toCOO, L&T RealtyAge43-50 yrsEducational QualificationBE CivilExperienceKey Requirements:Bachelor's...


  • Mumbai, Maharashtra, India BeBeeManufacturing Full time

    Job Overview As a Manufacturing Science & Technology Technical Manager, you will be responsible for leading and managing MS&T activities for Contract Manufacturing Organizations (CMOs). Ensure NVS product performance is monitored and maintained in a validated state. Support root cause investigations with MS&T intelligence on deviations, technical complaints,...


  • Mumbai, Maharashtra, India BeBeeManufacturing Full time

    Job Overview As a Manufacturing Science & Technology Technical Manager, you will be responsible for leading and managing MS&T activities for Contract Manufacturing Organizations (CMOs).Ensure NVS product performance is monitored and maintained in a validated state.Support root cause investigations with MS&T intelligence on deviations, technical complaints,...


  • Mumbai, Maharashtra, India General Mills Full time ₹ 12,00,000 - ₹ 36,00,000 per year

    Position TitleD&T Manager – Global ImpactFunction/GroupDigital & TechnologyLocationMumbai/PuneShift TimingRegularRole Reports toSr D&T ManagerRemote/Hybrid/in-OfficeHybridABOUT GENERAL MILLS We make food the world loves: 100 brands. In 100 countries. Across six continents. With iconic brands like Cheerios, Pillsbury, Betty Crocker, Nature Valley, and...


  • Mumbai, Maharashtra, India Cozzera Full time ₹ 15,00,000 - ₹ 20,00,000 per year

    Job Title: MS SQL Database ArchitectExperience: 6 yearsLocation: RemoteJob Type: Full-TimeProject required to work upon:Split the one big SQL DB into multiple smaller DB and maintaining the entity sanctitySQL Scripting and versioning process to the releaseMigrate East DB data to west DB and eliminate east DBOnce DB is split migrate data to MongoDB (This...


  • Mumbai, Maharashtra, India Apotex Inc. Full time ₹ 12,00,000 - ₹ 24,00,000 per year

    About Apotex Inc.Apotex is a Canadian-based global health company. We improve everyday access to affordable, innovative medicines and health products for millions of people worldwide, with a broad portfolio of generic, biosimilar, innovative branded pharmaceuticals and consumer health products. Headquartered in Toronto, with regional offices globally,...


  • Mumbai, Maharashtra, India Apotex Full time ₹ 12,00,000 - ₹ 24,00,000 per year

    About Apotex Inc.Apotex is a Canadian-based global health company. We improve everyday access to affordable, innovative medicines and health products for millions of people worldwide, with a broad portfolio of generic, biosimilar, innovative branded pharmaceuticals and consumer health products. Headquartered in Toronto, with regional offices globally,...

  • D&T Project Manager

    5 days ago


    Mumbai, Maharashtra, India General Mills Full time ₹ 12,00,000 - ₹ 24,00,000 per year

    Job Description:Position TitleD&T Project ManagerFunction/GroupDigital & TechnologyLocationMumbai- PowaiShift TimingRegularRole Reports toManager - PMORemote/Hybrid/in-OfficeHybridABOUT GENERAL MILLSWe make food the world loves: 100 brands. In 100 countries. Across six continents. With iconic brands like Cheerios, Pillsbury, Betty Crocker, Nature Valley, and...