Formulation and Process Design

4 days ago

Chennai Tamil Nadu, India Pfizer Full time

Description ROLE SUMMARY

ROLE RESPONSIBILITIES

Work with Pfizer project scientist to understand the challenges and needs when developing drug-dosage forms (tablets, capsules, ointments/creams, multiparticulate beads, etc.). Identify opportunities to use engineering knowledge and computational tools to help solve project challenges. Be able to work independently, with mínimal supervision, to define the problem statement, then develop and execute a modeling work plan to solve the issue.

Using a variety of computational techniques, develop predictive tools and models to support drug development/manufacturing efforts for the Pfizer portfolio. Modeling techniques include (but not necessarily limited to): Finite Element Analysis, discrete element method (DEM), data science & statistical techniques, computational fluid dynamics (CFD), population-balance models (PBM), and first-principles engineering models.

Communicate and present results internally at meetings and, on occasion, at external forums. Present scientific results to a diverse audience through data analysis and visualizations. Support Pfizer’s key technology platforms: continuous tablet manufacturing and multiparticulates, via computational modeling.

Work with external partners (e.g., universities, research organizations) and vendors (e.g., software companies) to execute and deliver well-defined modeling projects.

BASIC QUALIFICATIONS

Education/Experience

Post-graduate qualification (PhD) in relevant field e.g. chemical, mechanical, pharmaceutical engineering with focus on process modelling. Strong background in numerical methods, programming, and mathematics. Graduate research must be focused on computational modeling of powder compression, stress analysis and solid mechanics. Proficiency in open source and commercially available FEA simulation software, Python and Matlab programming will be very desirable. Must demonstrate good problem-solving skills.

Excellent organizational skills: ability to manage several projects simultaneously and deliver

results in a timely manner. Excellent interpersonal skills: work effectively as part of cross functional teams and embrace teamwork. Excellent written and verbal communication skills: must be able to communicate ideas and results with colleagues with diverse backgrounds. Demonstrated track record of publications, presentations, and/or patents.

PREFERRED QUALIFICATIONS

momentum, and energy transport phenomenon; and a mathematical ability to setup and solve

linear, non-linear, and differential equations. Strong programming/coding skills and experience

with numerical techniques is required. Proficient in programming using some standard

language: C/C++, Python, R, Matlab, etc. Must be familiar working in a high-performance-computing environment (Linux based). Experience with any of the following software is preferred: ABAQUS,, ANSYS, OpenFOAM, STAR-CCM+, other closely related packages. Knowledge of data analysis and visualization packages (e.g., Spotfire or Tableau) is desirable. Strong statistical skills are also preferred.

Work Location Assignment: Flexible

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

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