Formulation And Process Design – Process Modeller

Description ROLE SUMMARYThe drug-product process-modeling team in Worldwide R D Pfizer seeks a Senior Scientist PhD level to develop new computational models tools to support the end-to-end development of drug-dosage forms tablets capsules microsphere beads ointments creams oral liquids etc The successful candidate will use modeling and simulation techniques to solve pharmaceutical industrial research problems related to batch and continuous manufacturing with special emphasis on powder flows mixing processing and compaction Experience with computational techniques is required such as FEA stress analysis process models and statistical techniques population-balance models PBM computational fluid dynamics CFD and engineering models Applicants must have a post-graduate qualification PhD degree in Chemical Engineering Mechanical Engineering Process Control Engineering or related discipline with a focus on the modeling of powder granular compaction using FEA and DEM Close collaboration with Pfizer project scientists is essential - candidates must have excellent communication skills and be able to identify opportunities to apply modeling to develop drug products This full-time position is based in Chennai India ROLE RESPONSIBILITIESWork with Pfizer project scientist to understand the challenges and needs when developing drug-dosage forms tablets capsules ointments creams multiparticulate beads etc Identify opportunities to use engineering knowledge and computational tools to help solve project challenges Be able to work independently with minimal supervision to define the problem statement then develop and execute a modeling work plan to solve the issue Using a variety of computational techniques develop predictive tools and models to support drug development manufacturing efforts for the Pfizer portfolio Modeling techniques include but not necessarily limited to Finite Element Analysis discrete element method DEM data science statistical techniques computational fluid dynamics CFD population-balance models PBM and first-principles engineering models Plan and execute experimental studies in collaboration with experimental experts to support validate modeling efforts Work with Pfizer scientists to apply and implement modeling tools into project workflows Communicate and present results internally at meetings and on occasion at external forums Present scientific results to a diverse audience through data analysis and visualizations Support Pfizers key technology platforms continuous tablet manufacturing and multiparticulates via computational modeling Work with external partners e g universities research organizations and vendors e g software companies to execute and deliver well-defined modeling projects BASIC QUALIFICATIONSEducation ExperiencePost-graduate qualification PhD in relevant field e g chemical mechanical pharmaceutical engineering with focus on process modelling Strong background in numerical methods programming and mathematics Graduate research must be focused on computational modeling of powder compression stress analysis and solid mechanics Proficiency in open source and commercially available FEA simulation software Python and Matlab programming will be very desirable Must demonstrate good problem-solving skills Excellent organizational skills ability to manage several projects simultaneously and deliverresults in a timely manner Excellent interpersonal skills work effectively as part of cross functional teams and embrace teamwork Excellent written and verbal communication skills must be able to communicate ideas and results with colleagues with diverse backgrounds Demonstrated track record of publications presentations and or patents PREFERRED QUALIFICATIONSCandidate must be proficient in fundamental engineering physical concepts such as mass momentum and energy transport phenomenon and a mathematical ability to setup and solvelinear non-linear and differential equations Strong programming coding skills and experiencewith numerical techniques is required Proficient in programming using some standardlanguage C C Python R Matlab etc Must be familiar working in a high-performance-computing environment Linux based Experience with any of the following software is preferred ABAQUS ANSYS OpenFOAM STAR-CCM other closely related packages Knowledge of data analysis and visualization packages e g Spotfire or Tableau is desirable Strong statistical skills are also preferred Work Location Assignment FlexiblePfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates Research and Development LI-PFE