Senior Bioinformatics Scientist

3 days ago


Bengaluru, India Loopworm Full time

About LoopwormLoopworm is building the next frontier in recombinant protein production using our novel LoopBac™ platform — an optimised system that uses insects as miniature bio-factories instead of conventional cell culture methods. This game-changing technology enables complex protein production at a fraction of the cost and time.We are on the verge of a major breakthrough, and we’re looking for a Senior Scientist – Bioinformatics to join our R&D team and single-handedly drive our bioinformatics initiatives . You will report directly to the VP of R&D and act as the central point of expertise across multiple verticals.Key ResponsibilitiesYou will be the go-to bioinformatics expert, collaborating with cross-functional teams to enable faster, more accurate, and cost-effective recombinant protein production:Protein Production Optimisation Team – Provide DNA, gene, or protein sequence insights for any new protein of choice; coordinate with contractual gene synthesis partners for gene sequence validation and codon optimisation .Genetic Engineering & Molecular Biology Team – Support comparative genomics and virus–host interaction studies to enhance the platform.Downstream Process Optimisation Team – Advise on recombinant protein–host protein interactions , protein tagging, and purification strategies.QA/QC & Assay Team – Recommend appropriate kits, antibodies, and assays through protein–protein interaction studies .What are the problem statements you would be working onCodon Optimisation for Novel insect host expressionPromoter & Enhancer Sequence Identification and PredictionViral Vector Stability and Sequence OptimisationPost-Translational Modification (PTM) Mapping in novel insect hostIn-Silico Screening for Expression BottlenecksRequired Skills & ExperiencePhD/Master’s in Bioinformatics, Computational Biology, or a related field.5 years of hands-on experience in running bioinformatics pipelines for Protein/DNA analysis.Expertise in genetics, genomics, proteomics, and protein modelling databases.Preferred coding background in Python, R, Perl (or similar), with ability to adapt and work with outsourced software developers.Experience in protein sequence analysis , codon optimisation , and comparative genomics .Familiarity with AI tools in bioinformatics (preferred but not mandatory).Strong problem-solving skills and ability to work independently while coordinating with multiple teams.Preferred Tools / Platforms(Candidates with proficiency in any of the following — or equivalent alternatives — are encouraged to apply)Sequence Analysis & Databases : NCBI, UniProt, Ensembl, KEGG, PDBGenomics & Alignment : BLAST, Clustal Omega, MUSCLE, MAFFTProtein Modelling : AlphaFold, Swiss-Model, PyMOL, ChimeraData Analysis : Bioconductor, Galaxy, GeneiousAI/ML & Coding : TensorFlow/PyTorch (for bioinformatics), Python/R, Jupyter NotebooksWorkflow Tools : Nextflow, Snakemake, or similarWhy Join Us?Be part of an India-first biotech innovation .Work on a revolutionary platform with potential to disrupt multiple industries — biopharma, diagnostics, cosmetics, and more.Collaborate with passionate scientists, engineers, and entrepreneurs.Enjoy a fast-paced and innovation-driven culture.



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