
Process Innovator
1 day ago
Job Title: Development Chemist – Process Innovation
Department: R&D – Process Improvement
Industry: Pharmaceutical Synthesis
Purpose of the Role:
To spearhead and execute the development, optimization, and scale-up of robust, cost-effective, and regulatory-compliant chemical processes for Active Pharmaceutical Ingredients (APIs) and intermediates, ensuring seamless technology transfer from laboratory to industrial-scale production.
Key Responsibilities
- 1. Strategic Objectives
- Drive innovation by designing novel synthetic routes that align with project timelines and regulatory requirements.
- Contribute to process differentiation strategies that enhance the organization's scientific credibility and client value proposition.
- Collaborate with cross-functional teams (Analytical, QA/QC, Regulatory) to support integrated drug development solutions.
2. Operational Tasks
- Perform route scouting, literature research, and develop robust and scalable chemical processes using Quality by Design (QbD) principles.
- Conduct laboratory experiments for reaction optimization, impurity profiling, and process safety assessment.
- Prepare and review technical reports, Standard Operating Procedures (SOPs), and technology transfer documents.
- Ensure compliance with Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP) during laboratory-scale and pilot-scale operations.
- Participate in troubleshooting during scale-up or commercial production batches and provide technical support during client audits.
3. Financial Goals
- Optimize process economics by reducing cycle time, yield improvement, and minimizing raw material costs.
- Support cost estimation activities during project proposals or client Requests for Quotation (RFQs) by providing technical insights.
4. Team Management and Collaboration
- Guide junior team members on experimental planning, data interpretation, and documentation best practices.
- Promote a culture of safety, learning, and innovation within the team.
- Work closely with Program Management and Business Development to align project goals with customer expectations.
Qualifications & Experience
- M.Sc. in Organic Chemistry
- 3–9 years of experience in Process R&D, preferably in pharmaceutical synthesis organizations
- Hands-on expertise in synthesis, scale-up, impurity profiling, and technology transfer
- Familiarity with analytical techniques (HPLC, GC, NMR) and regulatory documentation
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