Oligo Synthesis Lead

5 days ago


Kollam, Kerala, India beBeeAnalytics Full time ₹ 90,00,000 - ₹ 1,20,00,000
Lead Synthesis and Analytics Specialist

Our organization is seeking a highly skilled professional to lead oligo synthesis and analytics for groundbreaking therapeutic and diagnostic programs.

  • Develop and implement automated solid-phase synthesis methods, ensuring efficient detritylation–oxidation cycles.
  • Scale up synthesis to meet the demands of mmol level production while maintaining coupling efficiency above 99%.
  • Purify and characterize oligos using advanced techniques such as HPLC, PAGE, CE, LC-MS, and UV-Vis spectroscopy.
  • Manage lab instrumentation, inventory, safety protocols, and Standard Operating Procedures (SOPs).
  • Drive cross-functional method development and quality control initiatives.
Qualifications:
  • Ph.D. in a relevant field with 2–5 years of experience in oligo synthesis and analysis.
  • Strong foundation in phosphoramidite chemistry, purification, and analytics.
  • Bonus: experience with modified or therapeutic oligos, digital PCR/BEAMing.


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