
Senior Toxicological Specialist
1 week ago
We are seeking an experienced professional to fill a senior position in toxicological risk assessment. The ideal candidate will have a strong understanding of toxicological and pharmacological principles, as well as experience with QSAR, read-across techniques, and scientific literature evaluation.
Key Responsibilities- Toxicological Risk Assessment:
- Evaluate impurities and excipients in pharmaceutical products to assess potential health risks.
- Structure-Activity Relationship (SAR) Evaluation:
- Analyze chemical structures using Structure-Activity Relationship methods, including Quantitative Structure-Activity Relationship (QSAR) models, to identify health hazards in unstudied compounds.
- Read-Across Evaluation:
- Identify structural analogues and develop scientific rationales to support read-across assessments for untested chemicals.
- Impurity Specification Development:
- Develop safety justifications for setting impurity specifications in pharmaceutical products.
- Literature Exploration:
- Conduct thorough reviews of publicly available scientific literature to support safety assessments for unstudied chemicals.
- Environmental Risk Assessment:
- Perform environmental risk assessments for pharmaceutical compounds in accordance with regulatory standards.
- Health Hazard Assessment:
- Conduct health hazard and risk assessments to address product quality issues and support decision-making for product recalls, when necessary.
- Master's degree in Pharmacology or Pharmacy, or PhD in Pharmacology/Toxicology
- Strong understanding of toxicological and pharmacological principles
- Experience with QSAR, read-across techniques, and scientific literature evaluation
The successful candidate will enjoy a competitive compensation package, opportunities for professional growth, and a dynamic work environment.
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