
Data Architect – Synthetic Testing Solutions
2 weeks ago
About the Role
We are seeking a Senior Data Scientist to design and implement intelligent frameworks for synthetic test data generation in support of clinical trials, regulatory submissions, and GxP-compliant systems.
This role will leverage AI/ML and Python automation to deliver high-quality, audit-ready datasets that reduce reliance on production data, accelerate testing cycles, and ensure compliance with FDA, EMA, and global regulatory standards.
Key ResponsibilitiesSynthetic Test Data Automation
- Build Python frameworks to generate synthetic clinical and operational datasets.
- Produce CDISC-compliant datasets (SDTM, ADaM) for data transformation, analysis, and reporting workflows.
- Simulate domain-specific datasets (adverse events, labs, demographics, drug exposure) with variability and referential integrity.
- Develop connectors for Define-XML, Pinnacle21 validation, and statistical programming workflows.
Ai/Ml In Data Generation
- Apply generative Ai (llms, Gans, diffusion models) to model realistic clinical scenarios.
- Create synthetic patient journeys across edc, ecoa, ctms, lims, and pv systems.
- Use Ai-driven automation to simulate rare or complex cases for stress and edge-case testing.
Compliance & Data Governance
- Ensure adherence to Gxp, 21 cfr part 11, hipaa, and gdpr standards.
- Implement anonymization/obfuscation while maintaining clinical and statistical fidelity.
- Produce validation protocols and documentation for audit and inspection readiness.
Collaboration & Integration
- Work with Clinical Data Management, Biostatistics, Pharmacovigilance, and Compliance teams to gather requirements.
- Embed test data generation into ci/cd pipelines, trial simulations, and automated validation environments.
- Partner with smes to validate ai-generated datasets for regulatory acceptability.
Bonus Points:
- Familiarity with simulation software tools.
- Understanding of Health Authority regulations.
The Successful Candidate Will Have
- A degree in computer science, bioinformatics or related field.
- Experience working with python and machine learning algorithms.
- Strong understanding of data structures and algorithms.
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