
Manufacturing Operations Manager
3 days ago
As a seasoned manufacturing professional, you will lead the successful implementation of our MES and L2 systems. You will ensure that site-specific manufacturing processes are accurately captured and reflected in the global solution.
Key Responsibilities- MES Implementation: Representing site-specific needs during design, configuration, and deployment.
- Validation Leadership: Leading IQ, OQ, PQ, UAT, and traceability matrix execution.
- Documentation Ownership: Managing GxP documentation (URS, FS, DS, test cases, validation plans/reports).
- MES Product Expertise: Maintaining deep knowledge of MES functionality and architecture.
- Front-End Support: Acting as the first point of contact for MES application issues and user support.
- Training & Adoption: Delivering training and ensuring user readiness for MES usage.
- Data Management: Supporting data collection, migration, and master recipe creation.
- Audit Readiness: Ensuring all documentation and systems are compliant and audit-ready.
- Bachelor's degree in Engineering - Information Technology, Computer Science, Production, Pharmaceutical Sciences, or a related technical field.
- Preferred: Master's degree with specialization in Industrial Automation, Pharmaceutical Technology or related fields
- Specific Certification : GAMP 5 for system validation in regulated environments.
- CSV (Computer System Validation) for compliance with GxP.
- MES Platform Certifications e.g., Werum PAS-X, Siemens Opcenter, or Rockwell
- 21 CFR Part 11 Compliance Training for electronic records and signatures
- 6 to 8 years of experience
Strong understanding of pharma shop floor operations and regulatory requirements.
Prior hands-on experience with MES platforms or similar systems in GxP-regulated environments.
Proven experience in validation documentation and execution, especially for GxP Category 4 & 5 systems.
Experience in resolving front-end MES issues and supporting end-users post-deployment.
Familiarity with audit processes and documentation expectations
Skills- MES system configuration, deployment, and validation
- Front-end application troubleshooting and user support
- GxP and 21 CFR Part 11 compliance
- Validation protocol development and execution (IQ, OQ, PQ, UAT)
- Documentation management (URS, FS, DS, traceability matrices)
- Data migration and master recipe creation
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