
Senior Expert Data Science, Modeling
2 days ago
Your responsibilities will include, but are not limited to:
- Act as the M&SData Sciencerepresentative ondrug discoveryand lead optimizationprograms by collaboratively contributing to project team discussions,using dry- and wet-lab data toprovide scientific and strategic inputtoguidedecisions such ascompound progression and in vivo study prioritization
- Master and advocate the use of in silico models and in-house tools,applicationsand datato accelerate and streamline decision making
- Apply data mining to understand relationships between structure and molecular propertiesfor programs involving small molecules, peptides, RNAs
- Identifyopportunities tocreatecustom, project- or modality-specific in silico models and data strategy, and contribute to their developmentand implementation
- Proactively seek opportunities to increase the impact and awareness ofM&S Data Sciencethroughclear and concisecommunications with internal and external audiencesor variousexpertise
- Monitor and stay up to date on developments within the fieldof AI/ML applied to ADME and PK/PD, anddata science methodsappliedto drug discovery
Role requirements
Essentialrequirements:
- Advanced degree in life scienceswithmultidisciplinary background (cheminformatics, bioinformatics, biomedical engineering, AI/ML in drug discovery or life sciences, data science, computational biology,computationalchemistryor related field)
- PhD with 2+ years or MSc with 6+ years of relevant work experiencewith deep knowledge on drug discovery and development processes
- Experience in the application of(reproducible)data science methods,toolsand practicesto drug discovery
- Strong understanding of statistics,machine learning and deep learning
- Demonstrated knowledge of data visualization and exploratory analysis
- Solid skills in programming languages,i.e.Python and R, including software developmentpractices suchas version control, testing, documentation, etc.
- Knowledge of machine learning/deep learning libraries such as scikit-learn,kerasorpytorch
- Excellent communication skills and ability to translate analytical concepts for diverse audience and stakeholders (English is our primary language)
Desirable:
- Expertisewith discovery-stage PK modeling for small molecule compounds (e.g., relating ADME properties to in vivo PK; scaling of preclinical PK to human)is a plus
- Experience with generative algorithms and explainable AI
Languages :
- English.
Skills Desired
Chemistry, Clinical Pharmacology, Clinical Research, Drug Discovery, Initiative, Medical Research, Patient Care, Physiology, Quality Control, R&D (Research And Development), Simulation Software, Translational Medicine
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