Scientist III
1 month ago
Description
Who is USP?
The U.S. Pharmacopeial Convention (USP) USP is an independent scientific organization that collaborates with the world's top experts in health and science to develop quality standards for medicines, dietary supplements, and food ingredients. USP's fundamental belief that Equity = Excellence manifests in our core value of Passion for Quality through our more than 1,100 talented professionals across five global locations to deliver the mission to strengthen the supply of safe, quality medicines and supplements worldwide.
Brief Job Overview
The role is engaged in the delivery of USP Reference Standard candidate materials (API Impurities) through development of cost-effective synthetic routes. Candidate should carry literature search using scientific databases and works on design, planning and execution of synthesis of target molecules in mg to multigram/KG scale. Canddiate should optimize key reactions and develops scalable process and develop control strategies using PAT. As project team member, ensures the completion of assigned tasks as per timelines, communicates with the team and update on the project progress. They are also responsible for making project reports and technology transfer documents. They should be adherent to QMS and lab safety guidelines. They should possess excellent organizational, communication, and interpersonal skills.
How will YOU create impact here at USP?
The successful candidate must demonstrate proficiency on the following activities.
Plan, execute and complete the projects as per the timelines.
Carry out proper literature search related to assigned projects using various scientific data base.
Design synthetic routes for the target molecules and prepare project proposals with tentative cost estimations.
Perform the reactions in small as well as large scale in the lab for the synthesis of target compounds and purification of compounds through various techniques such as crystallization, column chromatography, and advanced flash purification systems.
Identify and troubleshoot synthesis and purification challenges
Interpretation of analytical data of synthesized compounds by IR, NMR, Mass Spectra, Elemental analysis etc.
Document all experiments conducted as per guidelines.
Work on any other assigned lab management responsibilities.
Conversant with lab safety norms and strictly follow them.
Learn and practice Diversity, Equity, Inclusion & Belonging culture. Who USP is Looking For? The successful candidate will have a demonstrated understanding of our mission, commitment to excellence through inclusive and equitable behaviors and practices, ability to quickly build credibility with stakeholders, along with the following competencies and experience:
Scientist III/IV – Ph.D (Synthetic Organic Chemistry) from a reputed group with minimum 0-5 years post-doctoral/industrial research experience in organic synthesis.(Or)M Sc (Organic Chemistry) from a reputed university with minimum 6-10 years of industrial experience in Pharmaceutical Process R&D or CRAMS or CRO set up (or) organic synthesis.
Strong background in synthetic organic chemistry, Interpretation of spectral data of compounds based on IR, NMR, HPLC, Mass, Elemental analysis and other analysis.
Ability to independently search literature, design, optimize and develop synthetic processes for any given target molecules/APIs.
Hands on experience in process development of diverse chemical class of APIs/ NCEs on lab scale.
Excellent troubleshooting skills in synthesis and purification of target compounds.
Should possess good verbal and written communication skills.
Should possess good organizational, communication, and interpersonal skills.
Additional Desired Preferences
Extensive knowledge on various types of organic reactions, and practical experience in handling various chemicals/reagents.
Track record of patents/ publications in synthetic organic chemistry/ process development.
Should have exposure to GMP/GLP environment and documentation procedures. Have good practical, documentation & presentation skills.
Meticulous attention to detail, as well as outstanding critical thinking and problem-solving skills.Demonstrated ability to work both independently and as a member of a team, show initiative, solve problems, prioritize the activities, and meet deadlines.
Supervisory Responsibilities
Not Applicable.
Benefits
USP provides you with the benefits you need to protect yourself and your family today and tomorrow. From company-paid time off, comprehensive healthcare options to retirement savings, you can have peace of mind that your personal and financial wellbeing is protected.
COVID-19 Vaccination Policy (will apply to the selected candidate(s) hired):
As a condition of employment with the United States Pharmacopeial Convention's (USP) duty to provide and maintain a workplace free of known hazards, all employees and contingent staff hired after July 1st, 2021, must be fully vaccinated unless a reasonable accommodation is approved. Your recruiter will advise accordingly.
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