Scientist Iii, Synthetics

2 weeks ago

Hyderabad, Telangana, India USP (U.S. Pharmacopeial Convention) Full time

Description


The Scientist-III - Synthetics Lab is engaged in development of novel and cost-effective synthetic routes for APIs and related compounds via conventional and/or continuous flow mode.

He/She carries literature search using scientific databases and works on design, planning and execution of synthesis of target molecules in mg to multigram/KG scale.

He/she optimizes key reactions and develops scalable process amenable for flow synthesis and develop control strategies using PAT.

As project team member, ensures the completion of assigned tasks as per timelines, communicates with the team and update on the project progress.

He/She will also be responsible for making project reports and technology transfer documents.
He/She should be adherent to QMS and lab safety guidelines. He/she should possess excellent organizational, communication, and interpersonal skills

Responsible for carrying out literature search and propose synthetic routes for target reference materials

  • Design of synthetic routes for the new target molecules
  • Responsible for the synthesis of the products at diverse scales (milligram to multigram)
  • Experience in handling large scale reactions.
  • Thorough in trouble shooting problems encountered during the reaction sequence
  • Ability to work on more challenging and innovative projects
  • Try to improve lab quality management system
  • Conversant with lab safety norms
  • General Material balance, Process Flow Diagrams (PFD), Recovery of solvents, Selection of equipment etc.,
  • Characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis etc.
  • To execute and completes the projects as per the timelines.
  • Ensuring that the availability of chemicals, equipment and glass wares the projects and forward the purchase requisitions.
  • Periodic check of the assigned equipment to ensure that equipment is in good condition.
  • To follow QMS of USP
  • Responsible for preparation and review of SOPs, Protocols, Technology Transfer reports etc.
  • Responsible for review the records and documents
  • Responsible to ensure the calibrations of the equipment as per the schedule
  • Responsible for preparing, executing and completing IQ/OQ/PQ of new instruments
  • Maintenance of daily stock register for new synthetic store, issue of chemicals to the scientists and update in ERP system
  • Responsible for maintenance of rejection folder according to synthetic works flow
  • Adhere to DEIB practices and undergo relevant trainings
  • M Sc (Organic Chemistry) from a reputed university with minimum 78 years of industrial experience in Pharmaceutical Process R&D or CRAMS or CRO set up (or) PhD (Synthetic Organic Chemistry) from a reputed group with minimum 02 years postdoctoral or industrial experience
  • Strong background in synthetic organic chemistry, characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis etc.
  • Ability to independently search literature, design, optimize and develop synthetic processes for any given APIs/ Target molecules
  • Hands on experience in process development of diverse chemical class of APIs/ NCEs on lab scale to KG scale via conventional and/or continuous flow mode
  • Good at troubleshooting and address synthesis and purification issues
  • Basic knowledge of Flow Reactors
  • Should possess good verbal and written communication skills.
  • Good organizational, communication, and interpersonal skills
Additional Desired Preferences

  • Track record of patents/ publications in synthetic organic chemistry/ process development/ flow chemistry.
  • Should have exposure to GMP/GLP environment and documentation procedures. Have good practical, documentation & presentation Skills He/she possess excellent verbal and written communication skills
  • Should have experience in preparing, executing and completing IQ/OQ/PQ of new instruments
  • Meticulous attention to detail, as well as outstanding critical thinking and problemsolving skills
  • Demonstrated ability to work both independently and as a member of a team, show initiative, solve problems, prioritize and handle multiple tasks simultaneously, meet deadlines, and remain calm under pressure.
  • Excellent organizational, communication, and interpersonal skills.
  • Selfmanagement (i.e., motivation, dealing with pressure, adaptability) and the ability to project a professional, consistent image of confidence, integrity, honesty and competence.
  • Proven ability to work in a team
Supervisory Responsibilities

No

Benefits:

USP provides you with the benefits you need to protect yourself and your family today and tomorrow.

From company-paid time off, comprehensive healthcare options to retirement savings, you can have peace of mind that your personal and financial wellbeing is protected.

As a condition of employment with the United States Pharmacopeial Convention's (USP) duty to provide and maintain a workplace free of known hazards, all employees and contingent staff hired after July 1st, 2021, must be fully

  • Scientist III

    2 weeks ago

    Hyderabad, Telangana, India USP Full time

    Description Who is USP? The U.S. Pharmacopeial Convention (USP) USP is an independent scientific organization that collaborates with the world's top experts in health and science to develop quality standards for medicines, dietary supplements, and food ingredients. USP's fundamental belief that Equity = Excellence manifests in our core value of ...

  • Data Scientist Iii

    2 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist III, Medical

    1 month ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation.Data...

  • Data Scientist III, Revenue Forecasting

    1 month ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation.Data...

  • Data Scientist III, Revenue Forecasting

    4 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation.Data...

  • Scientist I, Ard

    2 weeks ago

    Hyderabad, Telangana, India USP (U.S. Pharmacopeial Convention) Full time

    DescriptionBrief Job OverviewThis is a non-supervisory position in USP-India's Analytical Research & Development Laboratory. In this role, the Scientist - I is responsible for providing NMR support for characterization or identification samples received from various laboratories of USP India such as ARD, Synthetic chemistry, RSL, Verification, CDL and...

  • Data and Applied Scientist

    2 weeks ago

    Hyderabad, Telangana, India Microsoft Full time

    Our product is an LLM assistant with data first features and functionality We need leadership in how we design, build, and measure new capabilitiesResponsibilities:Responsibilities include designing business objectives, data goals, creating and maintaining synthetic data pipelines, creating data for fine tuning models, and leveraging customer usage for...

  • Data Scientist III, Medical T500-11851

    2 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation. Data...

  • Data Scientist III, Medical

    4 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation.Data...

  • Data Scientist III, Medical

    1 month ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist III, Medical

    4 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data and Applied Scientist

    2 weeks ago

    Hyderabad, Telangana, India Microsoft Full time

    OverviewThe Mobile Experiences Platform (MXP) division at Microsoft IDC is on a journey to create amazing AI experiences using LLM applications in the mobile space to offer useful, simple, and on-the-go intelligence. LLMs are creating opportunities that were completely out of reach for technology solutions only a year ago. Our team is capitalizing on this...

  • Data and Applied Scientist

    2 weeks ago

    Hyderabad, Telangana, India Microsoft Full time

    Overview The Mobile Experiences Platform (MXP) division at Microsoft IDC is on a journey to create amazing AI experiences using LLM applications in the mobile space to offer useful, simple, and on-the-go intelligence. LLMs are creating opportunities that were completely out of reach for technology solutions only a year ago. Our team is capitalizing on...

  • Data Scientist Iii, Bia Gps India Operations

    2 weeks ago

    Hyderabad, Telangana, India Bristol-Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist III, Development Operations T500-11858

    2 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    BMS Hyderabad is an integrated global hub where our work is focused on helping patients prevail over serious diseases by building sustainable and innovative solutions. This important science, technology, and innovation center will support a range of technology and drug development activities that will help us usher in the next wave of innovation.Data...

  • Data Scientist III, Revenue Forecasting

    4 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist III, Revenue Forecasting

    1 month ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist III, Revenue Forecasting

    1 month ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist III, Revenue Forecasting

    4 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...

  • Data Scientist Iii

    2 weeks ago

    Hyderabad, Telangana, India Bristol Myers Squibb Full time

    Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the...