Associate Scientist

2 weeks ago


Bengaluru, India Syngene Full time

JOB DESCRIPTION

Designation: Associate Scientist/Senior associate scientist

Job Location: Bangalore

Department: Discovery Biology

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose:

To be a part of the Assay Biology group and support various assay related activities involving protein biochemistry, cell biology techniques to evaluate or develop methods for screening assays, delineation of the mechanism of action by biochemical, enzyme assays using different assay technologies.

Key Responsibilities:

Assay development and validation for regular screening of molecules in different assay formats such as like Luminescence, fluorescence, FRET, radio assays, etc. Provide assistance to team leads in terms of planning and executing biochemical and/or cellular laboratory experiments and interpreting results. Regular cell culture activities like propagation and maintenance of cell lines and other operational activities in the labs Writing of Laboratory notebooks following ALCOA++ data integrity principles Ensure completion of the work as per the project timelines Must be able to update the reporting manager periodically and escalating any major shortfalls with respect to resources and timelines Able to train junior team members to execute screening activities with established SOPs Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety and attend relevant training imparted company

Educational Qualification:

M.Sc/M.Tech in Biological Sciences Expertise and in-depth knowledge of cell-based and biochemical assays (TR-FRET, HTRF, Fluorescence Intensity, Alpha screen, Radioactive assays and Luminesce based assays) Experience and good knowledge on assay QC parameters Experience in biophysical assays is plus Experience with automated liquid handling systems Experience in ELISA and Luminex based assays for cytokine estimations would be advantage Experience with human primary cells and tissue samples Experience with RT-PCR and Western blots; Knowledge of WES and JESS systems is a plus Ability to analyse and present data using excel, ppt and statistical tools (Graph Pad Prism, Excel-fit) Ability to plan and execute work and perform multiple activities in parallel.

Experience:

M.Sc/M.Tech with 3 to 8 years of experience

Behavioral Skills:

Good interpersonal skills, and the ability to work effectively in a team environment. Willingness and flexibility to work in cross functional teams across technical domains General ability to thrive in a growing infrastructure and culture and also think out of box approach when troubleshooting and problem solving.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.



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