Junior Research Fellow-1

Job Details

Position: Exploring the role of insulin-like growth factor-1 receptor IGF-1R signalling in escape from therapy-induced senescence-a novel therapeutic target to prevent adaptive resistance in breast cancers

Job Id: 3657

School: School of Natural Sciences (SNS)

Department: Life Sciences

Job Type: Contract

End Date: December 10, 2025

Applications are invited from interested and motivated candidates for the post of Junior Research Fellow-1 (JRF-1) in a time-bound research project for a temporary period, purely on a contractual basis as per the following details.

Project Title: "Exploring the role of insulin-like growth factor-1 receptor IGF-1R signalling in escape from therapy-induced senescence-a novel therapeutic target to prevent adaptive resistance in breast cancers".

The project will be conducted under the supervision of Dr. Anindita Chakrabarty, Associate Professor, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence (Deemed to be University), Delhi NCR.

Eligible and interested candidates should send their application with a complete CV (having personal and academic details, academic qualifications with percentage of marks or GPA, research experiences, publications, name, affiliation, and email address of at least two referees) to Dr Anindita Chakrabarty ) on or before 10th December 2025. Scanned copies of mark sheets/transcripts/testimonials/certificates, a recent passport-size photograph, and other relevant documents are also requested to be attached. Only the short-listed candidates will be contacted for an interview on/before 20th December 2025. No TA/DA will be provided to the candidates to attend the interview.

• Essential Qualification: S. 4-year program/BPharm/MBBS/Integrated BS-MS/MSc/BE/BTech or equivalent degree, with 55% marks and passing of NET/GATE test. from a recognized university. Candidate must be GATE/NET qualified (attach a copy of the scorecard).

Desirable qualification: Experience in cell, molecular biology and biochemical assays, animal (rodent) handling.

• Fellowship: Rs 37,000/p.m. +HRA (if hostel not provided).

• Duration of the Project: 1 year (temporary), can be extended further based on satisfactory performance in the first year.

4. Application deadline: 20th December 2025.

• Age limit: 28 years. The upper age limit can be relaxed up to 5 years in the case of candidates belonging to the scheduled castes/tribes/OBC, women and physically handicapped candidates.

• Project Description

Therapy resistance accounts for 90% of cancer-related deaths. Therapy-induced senescence helps cancer cells escape the cytotoxic effects of treatments by allowing a temporary cell cycle arrest. The project aims to understand the role of insulin-like growth factor-1 signaling in the re-entry of therapy-induced senescent breast cancer cells into the cell cycle and explores the potential to target this pathway to prevent therapy resistance through senescence induction.

• Nature of work

Junior Research Fellow-1 (JRF-1) will be responsible for conducting cell and molecular biology experiments, performing biochemical assays, and performing in vivo work for the project. It is expected that the JRF, after receiving proper training, will maintain the instruments and train undergraduate students in the lab.

About Shiv Nadar Institution of Eminence (SNIoE)

Shiv Nadar Institution of Eminence () is a student-centric, multidisciplinary and research-focused University offering a wide range of academic programs at the Undergraduate, Master's and Doctoral levels. The University was set up in 2011 by the Shiv Nadar Foundation, a philanthropic foundation established by Mr. Shiv Nadar, founder of HCL. The University is in the quest to become a globally acclaimed center for learning and innovation in the fields of Engineering, Natural Sciences, Humanities & Social Sciences, and Management. The core of the University comprises a select group of world-class faculties with doctoral and postdoctoral experience from ranked universities worldwide.

Shiv Nadar Institution of Eminence has recently been selected as one of the ten private Institutions of Eminence by the Government. In the NIRF (Government's National Institutional Ranking Framework), the University has been the youngest institution in the 'top 100' Overall list. In NIRF-2022, it ranked 61 in the 'University' category. Shiv Nadar University has been accredited with a Grade 'A' by NAAC (National Assessment and Accreditation Council), valid for five years from 26 November 2019. It is also among a select group of greenfield institutions in the country that was awarded the prestigious Atal Incubation Center grant by the NITI Aayog, Government of India, in the very first round in 2017.

The Department of Life Sciences is committed to pursuing research on fundamental and applied problems of Biomedical Sciences through an interdisciplinary research approach. The Department of Life Sciences has state-of-the-art laboratory infrastructure for conducting research in all innovative areas of Biomedical Sciences.