Chemist / Officer - Research & Development

1 day ago

Vadodara, Gujarat, India SDP HR Solution Full time ₹ 12,00,000 - ₹ 36,00,000 per year


Job Description:

Key Responsibilities

  • Process Development:

    • Design and execute multi-step organic synthesis experiments to develop new and innovative routes for API synthesis.

    • Conduct literature searches and patent reviews to identify non-infringing and commercially viable synthesis routes.

    • Optimize reaction parameters such as temperature, pressure, time, and solvent to improve yield, purity, and reduce costs.

  • Technology Transfer:

    • Prepare and document process development reports and technology transfer documents (TTDs) for seamless scale-up.

    • Collaborate with pilot plant and manufacturing teams to successfully transfer developed processes.

    • Provide technical support and troubleshoot issues during scale-up and commercial production batches.

  • Analytical and Data Management:

    • Utilize and interpret analytical data from instruments like HPLC, GC, NMR, Mass Spectrometry, and IR to monitor reactions and characterize products.

    • Ensure all experimental data and observations are meticulously recorded in a laboratory notebook, maintaining Good Laboratory Practices (GLP).

    • Compile stability data and other technical documents required for regulatory filings (e.g., Drug Master Files or DMFs).

  • Impurity Profiling:

    • Identify, synthesize, and characterize impurities and degradation products to ensure product quality and regulatory compliance.

    • Conduct forced degradation studies to understand the stability profile of APIs.

  • Collaboration & Communication:

    • Work closely with cross-functional teams including Analytical R&D (AR&D), Quality Assurance (QA), Quality Control (QC), and Regulatory Affairs.

    • Communicate project progress, challenges, and results to the R&D Manager and other stakeholders.

    • Mentor junior team members and contribute to a positive and collaborative work environment.

  • Safety & Compliance:

    • Adhere to all safety protocols and company policies, especially when handling hazardous or sensitive chemicals.

    • Maintain a clean and organized work area and ensure proper maintenance and calibration of laboratory equipment.

    • Stay updated on the latest regulatory guidelines and industry trends.


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