Formulations Scientist

3 days ago

Hyderabad Telangana, India Sai Life Full time

**Summary of Job**

To be responsible for pre-formulation and preclinical formulation activities. To be responsible for designing the experiment under supervision and handling associated equipment's and operations along with interpretations.

**Key Responsibilities**

1.Ability to design and execute pre-formulation experiments like solubility, pKa, log P, dissolution, intrinsic dissolution, bulk density, flow indices, solid-state assessment, excipient compatibility etc.

2.Completely conversant with hands on experience and/or interpreting data from pre-formulation studies of a compound including physicochemical, bulk, surface and particle properties.

4.Reasonably conversant with hands on experience and/or interpreting data from solid-state equipment's like PXRD, MDSC, TG, DVS and other techniques like Polarizing and Hot-stage Microscopy and other dynamic image analysis techniques, specially during supporting solid form and salt screening.

5.An additional benefit would be to have operational experience of handling Particle size analyzer, HPLC, GC, Dissolution apparatus and Disintegration apparatus.

6.Ability to collate and scientifically present data & observations and provide scientific inputs in discussion with internal or external customers.

7.Proactively maintain the equipment's, facility and supporting systems as per established good lab handling processes, maintain requisite equipment and process SOPs and lean tools

8.Follow good documentation practices and have adequate exposure to record observations in Electronic Lab Notebook (ELN).

9.Proactive in aligning with new technologies and approaches to participate in continuous improvement needs of the business.

10.He/she should have sufficient knowledge chemical safety, comprehensive risk assessment of drug substance and safe handling.

**Qualification**M. Pharma, M.Sc. or M Tech with relevant specialization in Pharmaceutical Sciences

**Experience**1-5 years

**Key Competencies (Technical, Functional & Behavioral)**

**Technical & Functional**
- Sound experience of fundamentals of pre-formulation and approaches used for preclinical formulation development of compounds. Basic knowledge on developing clinical formulation would be an added plus.
- Demonstrated capability in having understanding to design and interpret data from PXRD, modulated DSC, TGA, DVS, Microscopy and working operations of HPLC, GC, FT-IR, NMR, Dissolution, BET and other physical and physicochemical characterization techniques. Hands-on operating would be an added plus.

**Behavioral**

Aptitude to learn and excel.

Proactive in technical & operational space.

Ability to work in cross-functional team environment.

Ability to contextualize the observations and attention to detailing.

Effective communication skills and absorbing attitude.

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