Scientist - Medicinal Chemistry

2 days ago

Hyderabad, India Cellix Bio Full time

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. You will help make an impact on people’s lives and change futures every day. We are equally committed to bringing out your best and fostering a collaborative workplace built on trust and respect.

We empower our people to take charge of their potential. We offer training and leadership development programs tailored to help you build valuable skills and succeed in your career. As you discover your potential, your professional and personal future will become brighter.

SCIENTIST - Medicinal Chemistry

Cellix Bio is hiring Scientists for Medicinal Chemistry department.

Education and experience required:
M.Sc (Organic/ General/ Industrial Chemistry) with 5-7 years of experience in drug discovery in medicinal chemistry. Capable of handling milligram to multigram scale reactions and doing multi step synthesis.
- In-depth understanding of physical pharmacy, physical chemistry, thermodynamics, chemical reaction kinetics is a must.
- In-depth understanding of various pre
- formulation and formulation studies including excipient compatibility, forced degradation studies and unit steps in formulation manufacture is a must.
- Experience with pilot-scale and manufacturing-scale equipment is a plus.
- Experience with process analytical technologies (PAT) is a plus.
- Conduct API, excipient, packaging or device characterization; excipient compatibility and forced degradation studies.
- Develop robust lab-scale, pilot-scale and commercial-scale manufacturing process based on Quality by Design (QbD) principles using design of experiments (DOE). Recommend stage appropriate acceptance criteria. Utilize PAT where feasible. Utilize relevant statistical tools, as required.
- Review and analyze relevant stability data from lab-scale, pilot-scale and commercial-scale, R&D and GMP stability studies by utilizing industry standard modeling and analysis tools including regression analysis for shelf-life prediction. Develop and implement strategies to control related substances, where applicable.
- Draft high-quality industry standard technical documents (protocols, reports, technical memorandums, position papers etc.).
- Independently draft and/or review standard operating procedures (SOPs).
- Maintain effective and pro-active communication and coordination of activities with multi-functional stakeholders.

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