Process Modeler

2 weeks ago

Chennai Tamil Nadu, India Pfizer Full time

Why Patients Need You

We are seeking a Process Modeler to join the Engineering Sciences group within Chemical Research and Development (CRD) in Chennai India. CRD, as part of Pfizer Research and Development (PRD) in the Pharmaceutical Sciences Small Molecule organization, is responsible for the development of process technology to manufacture active pharmaceutical ingredients (API). CRD scientists and engineers engage in all facets of development from small scale synthesis in support of Discovery programs, to the development of the commercial synthetic route. CRD colleagues partner with manufacturing specialists for API synthesis in kilo-lab and pilot plant facilities, as well as provide support for technology transfer to Pfizer manufacturing sites and third party facilities.

Role Responsibilities
- As a technical expert in computational fluid dynamics and multi physics models, play a leading role in the development of our strategy in process systems engineering and help establish systems engineering as a key factor in enhancing speed, quality and flexibility in the development of robust pilot and commercial manufacturing processes for intermediates and Active Pharmaceutical Ingredients.
- Use expertise to develop hybrid data driven and first principle models and methodologies, design model based experimental strategies to support process scaleup and optimization.
- Use parameter estimation, global sensitivity analysis, error propagation to optimize modelling approaches to help define the process design space and analyze the effects of process deviation on process performance.
- Develop process and equipment digital twins and models.
- Interface with scientific collaborators connecting the wider technology, business and academic institutions.
- Partner closely with other process modelers, statisticians, process chemists, chemical engineers and the wider academic community to develop skills and knowledge.
- Collaborate and author novel ad impactful publications and presentations.
- Independently plan, prioritize, interpret and present own work.
- Communicate effectively to project teams and line managers and present data at departmental technical governance meetings.

QUALIFICATIONS
- Ph.D. or equivalent in Chemical Engineering and Chemistry.
- Experience with Computational Fluid Dynamics, ideally with Lattice Boltzmann techniques and particle dynamics
- Experience with multiphase flows is desired
- Evidence of working in multidisciplinary scientific teams.
- Evidence of consistently high-quality performance.
- Experience in M-Star, ANSYS Fluent desired.
- Scientific programming experience, especiallyin Python, is desirable.
- Experience with process simulators like AspenPlus, gPROMS is a plus
- Model based Experimental Design, Multivariate Analysis and Bayesian optimization is desired

Work Location Assignment: Hybrid

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

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