Principal Scientist-ad

2 weeks ago

Ahmedabad Gujarat, India Piramal Pharma Solutions Full time

**Team Leadership and Mentorship**:
- Lead and manage a team of Research Associates (RA) and Junior Research Scientists, ensuring optimal productivity and skill development.

- Provide technical guidance in troubleshooting complex analytical instrument issues (HPLC, LC-MS, NMR, GC, IR) and resolve analysis problems independently.

- Mentor team members in advanced analytical techniques and guide them in troubleshooting experimental challenges.

**Project Coordination and Technical Execution**:
- Oversee the execution of complex projects, ensuring that experiments are designed and carried out in accordance with client requirements and project objectives.

- Demonstrate expertise in developing robust analytical methods for various compounds, including method validation and process development for scale-up of APIs.

- Coordinate multiple projects by allocating resources effectively, monitoring timelines, and ensuring all data meet quality and regulatory standards.

**Advanced Analytical Interpretation**:
- Exhibit expert-level skills in interpreting complex analytical data from techniques such as NMR (structure elucidation), LC-MS (mass fragmentation patterns), HPLC (impurity profiling), GC (volatile analysis), and IR (functional group identification).

- Analyze complex impurity profiles, degradation pathways, and validate analytical methods for new molecules, ensuring high accuracy in results.

- Develop and refine process chemistry for compound scale-up, ensuring efficient and scalable synthesis routes with a clear understanding of analytical method development for each stage.

**Instrument Management and Troubleshooting**:
- Oversee the maintenance and troubleshooting of key analytical instruments like HPLC, LC-MS, GC, FT-IR, NMR, and others.

- Ensure instrument performance through regular calibration, preventive maintenance, and adherence to SOPs to minimize downtime and ensure consistent data quality.

- Train team members in the use of cutting-edge technology platforms, ensuring they remain proficient with the latest instrument functionalities and software updates.

**Cross-Departmental Technical Collaboration**:
- Collaborate with R&D, QA, EHS, and Projects teams to provide technical solutions to complex analytical and process-related challenges.

- Actively participate in technical discussions with the chemistry and process development teams to resolve issues related to method development and scale-up chemistry.

**Client Relationship Management and Technical Reporting**:
- Serve as the primary point of contact for clients, providing regular technical updates, addressing scientific concerns, and proposing adjustments to study design where needed.

- Generate comprehensive, high-level technical reports that include data interpretation, method validation outcomes, and process development summaries, tailored for client presentations.

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