Formulation Scientist

2 days ago

Ahmedabad Gujarat, India Zydus Group Full time

Department
- VTC R&D
- Job posted on
- Oct 24, 2024
- Employment type
- C-C5-Confirmed-R&D Staff

Job Overview:
Key Responsibilities:

- Design and develop vaccine formulations, including adjuvants, emulsions, nanoparticles, and combination products, with a focus on immune response enhancement and long-term stability.
- Conduct pre-formulation studies to evaluate the physicochemical properties of antigens, excipients, and adjuvants.
- Optimize formulations for immunogenicity, delivery, and scale-up, using advanced technologies such as emulsions, liposomes, and particulate systems.
- Perform stability testing at various conditions (e.g., temperature, humidity) and analyse data to ensure product shelf-life and safety.
- Collaborate with cross-functional teams, including process development, analytical, and regulatory departments, to ensure smooth transition from R&D to clinical manufacturing.
- Develop and implement robust manufacturing processes for scalable vaccine formulation production.
- Stay current on advancements in vaccine adjuvant technologies, delivery systems, and regulatory requirements.
- Prepare detailed technical reports, SOPs, and documentation for regulatory submissions.
- Support tech transfer activities for moving formulations from the lab to large-scale production.

Qualifications:
PhD or Master’s in Pharmaceutical Sciences, Biochemistry, Biotechnology, or related field with a focus on vaccine development or formulation science.

5-10 years of hands-on experience in vaccine formulation development.

Strong expertise in adjuvant systems (e.g., alum, squalene-based emulsions, saponins) and immune modulation strategies.

Experience in formulation stability studies and data analysis.

Familiarity with cGMP, GLP, and regulatory guidelines related to vaccine development.

Excellent problem-solving, communication, and teamwork skills.

Preferred Skills:
Knowledge of sterile formulation and lyophilization techniques.

Hands-on experience with characterization techniques (e.g., particle sizing, zeta potential, HPLC, DLS).

Familiarity with immunological assays (e.g., ELISA, flow cytometry) for evaluating vaccine efficacy

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