
Senior Organic Chemist
1 week ago
Job Overview: We are a non-profit research and development organization focused on discovering and developing innovative therapeutics, diagnostics, and devices for diseases with significant socio-economic impact. Our research has led to the creation of a portfolio of therapeutics in various stages of development, from early discovery to late-stage clinical trials.
Key Responsibilities:
- Design and execute synthetic routes to prepare small molecules for drug discovery programs
- Track structure-activity relationships (SAR) and optimize potency, selectivity, and properties of small molecules
- Perform purification and structural characterization of compounds
- Troubleshoot synthetic problems and optimize reaction conditions
- Provide guidance and mentorship to junior colleagues
- Maintain accurate lab records and contribute to technical reports
- Collaborate with analytical teams as needed
- Provide input on intellectual property activities
Required Qualifications:
- Master's or Doctoral degree in Organic Chemistry, Medicinal Chemistry, or a related field
- Postdoctoral experience in organic chemistry/medicinal chemistry (optional)
- 0-4 years of hands-on experience in working on bench, preferably in an industry
Technical Skills:
- Skilled in multistep organic synthesis, reaction optimization, and compound isolation
- Proficient in chromatography (TLC, column, flash), spectroscopic analysis (NMR, LC-MS, HPLC), and purification techniques (recrystallization, precipitation, others)
- High level of creativity and productivity with strong synthetic chemistry problem-solving skills
- Demonstrated excellence in organic synthesis, conversant with current literature
- Effective oral and scientific/technical writing communication skills
- Ability to work independently and collaboratively within a team
- Commitment to lab safety and adherence to safety protocols
- Familiarity with reaction databases (e.g., Reaxys, SciFinder)
- Proficiency using MS Office applications
Benefits: Competitive compensation package commensurate with experience.
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