
Data Scientist
2 days ago
Data Scientist - Synthetic Data Generation
We are seeking a highly skilled Data Scientist to design and implement intelligent frameworks for synthetic data generation in support of clinical trials, regulatory submissions, and GxP-compliant systems. This role will leverage AI/ML and Python automation to deliver high-quality, audit-ready datasets that reduce reliance on production data, accelerate testing cycles, and ensure compliance with FDA, EMA, and global regulatory standards.
Key Responsibilities
- Develop Python frameworks to generate synthetic clinical and operational datasets.
- Produce CDISC-compliant datasets (SDTM, ADaM) for data transformation, analysis, and reporting workflows.
- Simplify domain-specific datasets (adverse events, labs, demographics, drug exposure) with variability and referential integrity.
- Develop connectors for Define-XML, Pinnacle21 validation, and statistical programming workflows.
AI/ML in Data Generation
- Apply generative AI (LLMs, GANs, diffusion models) to model realistic clinical scenarios.
- Create synthetic patient journeys across EDC, eCOA, CTMS, LIMS, and PV systems.
- Use AI-driven automation to simulate rare or complex cases for stress and edge-case testing.
Compliance & Data Governance
- Ensure adherence to GxP, 21 CFR Part 11, HIPAA, and GDPR standards.
- Implement anonymization/obfuscation while maintaining clinical and statistical fidelity.
- Produce validation protocols and documentation for audit and inspection readiness.
Required Skills & Qualifications
- Strong Python expertise (pandas, NumPy, scikit-learn, PyTorch/TensorFlow).
- Hands-on experience generating synthetic clinical data or applying CDISC standards (SDTM, ADaM, Define-XML).
- Familiarity with clinical data management systems.
- Knowledge of GxP/21 CFR Part 11 and regulated data handling.
- Experience with test automation frameworks and validation tools.
Preferred Qualifications
- Background supporting clinical trial systems.
- Understanding of statistical workflows and integration into test pipelines.
- Cloud experience for secure AI/ML deployment.
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