
Nucleic Acid Chemistry Expert
1 day ago
Lead Oligo Synthesis and Analytics Specialist
About this Role:
You will be a key player in delivering cutting-edge solutions in genomics and beyond as a PhD-level Lead Oligo Synthesis and Analytics Specialist. Our team is shaping the future of diagnostics and therapies, and we need your expertise to drive precision-driven results.
Main Responsibilities:
- Routine and troubleshoot automated solid-phase synthesis (detritylation–oxidation cycles).
- Scale synthesis to mmol level with coupling efficiency greater than 99%.
- Purify oligos using HPLC, PAGE, and CE techniques, followed by characterization via LC-MS, UV-Vis, and MS analysis.
- Maintain lab instrumentation, inventory management, safety protocols, and standard operating procedures.
- Drive cross-functional method development and quality control initiatives.
Qualifications and Skills:
- Ph.D. + 2–5 years of experience in oligo synthesis and analysis.
- A strong foundation in phosphoramidite chemistry, purification techniques, and analytics is required.
- Bonus points for experience with modified or therapeutic oligos, digital PCR/BEAMing.
Why Join Us:
Be part of a pioneering team that's revolutionizing diagnostics and therapies. We offer meaningful scientific opportunities, growth prospects, and a supportive work environment.
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