Senior Bioprocessing Specialist

1 week ago

Bengaluru, Karnataka, India beBeeBiotechnology Full time ₹ 20,00,000 - ₹ 25,00,000
**Job Title:** Biotechnology Innovation LeaderOur team is pioneering a breakthrough in recombinant protein production using insects as miniature biofactories. This disruptive approach offers cost-effective, scalable, and sustainable protein manufacturing for life sciences, animal health, and beyond.We are seeking an experienced Principal Scientist to lead our Downstream Process Optimisation & Protein Purification team. The ideal candidate will oversee budget planning, strategy, and execution for downstream R&D activities, implement and validate virus removal/inactivation steps to meet global regulatory standards, and establish robust R&D processes.Requirements:- PhD or Master's degree in Biotechnology, Bioprocess Engineering, Biochemistry, or related field
- 7+ years of industry experience in Recombinant Protein Purification and Downstream Processing
- Proven track record of scaling up purification processes from R&D to commercial manufacturing
- Experience working with complex eukaryotic expression systems, preferably insect-based
- Familiarity with IP processes and working with legal/IP teams
Key Responsibilities:- Lead a high-impact team in a fast-growing biotech company
- Oversee budget planning, strategy, and execution for downstream R&D activities
- Implement and validate virus removal/inactivation steps to meet global regulatory standards
- Translate research protocols to commercial-scale processes, collaborating closely with the commercial production team
- Establish and maintain robust R&D processes, ensuring timelines and milestones are met
- Participate in recruitment, training, and development of team members
Required Skills & Experience:- Chromatography Systems - AKTA or equivalent FPLC/HPLC systems for affinity, ion exchange, hydrophobic interaction, and size exclusion chromatography
- Tangential Flow Filtration (TFF) / Ultrafiltration Units - Protein concentration, buffer exchange, and diafiltration at R&D and pilot scale
- Virus Removal & Inactivation Equipment - Depth filtration units, virus filtration modules, and chemical inactivation setups
- Bioreactor Harvest & Clarification Systems - Continuous and batch clarification units suitable for insect biomass processing
- Clean-In-Place (CIP) & Steam-In-Place (SIP) Systems - For maintaining GMP compliance in purification operations

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