Upstream Cell Culture Specialist

2 days ago

Hyderabad Secunderabad Telangana, India beBeeBioprocessing Full time ₹ 7,00,000 - ₹ 12,00,000

Job Description

">Upstream Process Development Specialist

We are seeking a highly skilled Upstream Process Development Specialist to join our team. As an expert in cell culture and upstream processing, you will be responsible for developing and optimizing processes for biologics production.

Your primary focus will be on designing and executing experiments to improve cell growth, productivity, and product quality attributes. You will work closely with cross-functional teams to ensure seamless integration into end-to-end biomanufacturing workflows.

Key Responsibilities:

  • Develop and optimize upstream cell culture processes, including media formulation, feeding strategies, and bioreactor control parameters.
  • Perform small-scale, bench-scale, and pilot-scale experiments to support process development and solving.
  • Assess and incorporate single-use bioreactor systems and technologies to enhance process flexibility and efficiency.

Requirements

Qualifications

To be successful in this role, you will need the following qualifications:

  • Ph.D., M.S., or B.S. in Biotechnology, Biochemical Engineering, Molecular Biology, or a related field with a focus on cell culture and upstream processing.
  • 3+ years of experience in upstream process development for biologics, including hands-on experience with mammalian or microbial cell culture systems.
  • Proficiency in working with single-use bioreactor systems is highly preferred.
  • Familiarity with fed-batch, perfusion, and continuous culture processes.
  • Solid understanding of bioreactor design, operation, and process control strategies.
  • Proficiency with process monitoring tools and analytical instrumentation for cell culture.
  • Excellent problem-solving and analytical skills with the ability to manage sophisticated data sets.
  • Strong written and verbal communication skills, with experience communicating technical data to diverse audiences.
  • Experience with cGMP guidelines, regulatory standards, and technology transfer in biomanufacturing.
  • Knowledge of cell line development and characterization.
  • Familiarity with automation, PAT (Process Analytical Technology), and data-driven optimization tools.
  • Lead numerous projects simultaneously and meet aggressive timelines.
  • Demonstrated ability to lead multiple collaborators and conflicting goals.
  • Business-level proficiency in English (verbal/written) and proficiency in Excel and presentation skills.
  • Willingness to travel as required.
  • Self-motivated, team-oriented, collaborative and skilled in working in a matrixed and multi-functional environment.
  • Good social skills (oral and written).

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