
Senior Synthesis Chemist
2 weeks ago
Job Summary:
This is a challenging opportunity for an experienced Research Scientist to join our team and contribute to the discovery and development of novel therapeutics, diagnostics, and devices for diseases with a high socio-economic impact.
Key Responsibilities:
- Design and execute synthetic routes to prepare small molecules for drug discovery programs.
- Track SAR and optimize potency, selectivity, and properties of small molecules for research programs.
- Purify and structurally characterize compounds.
- Troubleshoot synthetic problems and optimize reaction conditions.
- Provide mentorship and guidance to junior colleagues.
- Maintain accurate lab records and contribute to technical reports.
- Collaborate with analytical teams as needed.
- Contribute to intellectual property activities.
Requirements:
- A Master's degree in Organic Chemistry, Medicinal Chemistry, or a closely related field.
- A PhD in organic chemistry / medicinal chemistry.
- Postdoctoral experience in organic chemistry / medicinal chemistry (optional).
- 0-4 years of hands-on experience in working on a bench, preferably in an industry.
Technical and Soft Skills:
- Skill in multistep organic synthesis, reaction optimization, and compound isolation.
- Proficiency in chromatography (TLC, column, flash), spectroscopic analysis (NMR, LC-MS, HPLC), and purification techniques (recrystallization, precipitation, others).
- A high level of creativity and productivity with strong synthetic chemistry problem-solving skills.
- Demonstrated excellence in organic synthesis, conversant with the current literature.
- Effective oral and scientific/technical writing communication skills.
- An ability to work independently and collaboratively within a team.
- A commitment to lab safety and adherence to safety protocols.
- Familiarity with reaction databases (e.g., Reaxys, SciFinder).
- Proficiency using MS Office applications is required.
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