
Senior Drug Metabolism and Pharmacokinetics Expert
1 week ago
We are seeking a highly skilled Senior Scientist to join our team in the field of DMPK. The ideal candidate will have extensive experience in designing and executing studies to support antibody-drug conjugate (ADC) and monoclonal antibody (mAb) programs, from discovery through IND-enabling stages.
Key Responsibilities:
- Design and execute DMPK studies to support ADC and mAb programs
- Quantification of biologics using LC-MS/MS, MSD, and ELISA platforms
- Apply advanced bioinformatics tools such as BioPharma Finder, MaxQuant, Spectronaut, and other relevant analytical software
- Select ADC and mAb lead candidates based on DMPK profiling
- Interpret complex DMPK data and provide actionable insights
- Presentation and collaboration with cross-functional teams
The successful candidate will have a strong foundation in DMPK principles, including PK/PD, toxicology, and translational sciences. They will also possess excellent communication skills and be able to work effectively in a team environment.
Requirements:
- M.Sc. (Biochemistry / Pharmaceutical Chemistry) or Ph.D. with relevant experience
- 12-15 years of experience in DMPK or related field
- Expertise in quantification of biologics and bioinformatics tools
- Strong foundation in DMPK principles and toxicology
Competencies:
- Antibody, ADC characterisation
- Communication Skills
- Excel software Skills
- Interpersonal Skills
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