Unlocking Biology's Secrets

Synlico Inc. is at the forefront of making cellular processes explainable, predictable, and engineerable by leveraging causality.

We employ machine learning & deep learning, causal discovery & inference, and single-cell bioinformatics to unravel the causal relationships between cells' intracellular activities and their responses in patients' heterogeneous microenvironments.

Our technology has a broad range of potential vertical applications in drug discovery, including target identification, therapy design, manufacturing, and biomarker discovery.

• Conduct searches in public genomic databases (GEO, CellXGene, HumanCell Atlas).
• Distinguish different functional genomics technologies and biological experimental methodologies to match our needs.
• Understand necessary dataset qualifications.
• Enter matching datasets to the database accurately with utmost attention.
• Validate/cross-check new datasets to avoid duplicates or problems.
• Optimize database structure to optimize information flow.

• Ph.D. graduate in computational biology, bioinformatics, single-cell biology, genomics, immunology, biomedical engineering, or related field.
• Strong technical focus and knowledge of genomics, molecular biology, and technologies such as qPCR and next-generation sequencing.
• Demonstrated proficiency in analysis of large-scale transcriptomics data (especially scRNA-seq).
• Experience identifying outliers for gene expression and splicing from RNA-seq data.
• Experience working with relevant genomic databases and browsers and their annotations.
• Proficiency in Git operations.
• Strong coding and visualization skills using Python or R.
• Experienced in data wrangling using pandas or tidyverse.
• Skilled in Linux command-line interface (CLI) operations.
• Attention to Detail: Ability to ensure accuracy and spot discrepancies or duplications for data entry and validation.
• Dig to the bottom: Ability to track down correct data source and not be dissuaded by obstacles or incomplete information.
• Critical Thinking: Ability to assess, analyze, and question information critically is essential.
• Consistency: Ability to deliver steady and reliable results in given timeframe.
• Good command of English speaking and writing.