
Leading Oligo Synthesis Scientist
3 days ago
Job Opportunity: Synthesis Scientist
We are seeking a highly skilled Synthesis Scientist to lead our oligo synthesis and analytics efforts.
The ideal candidate will have a strong background in phosphoramidite chemistry, purification, and analytics.
Key Responsibilities:
- Run and troubleshoot automated solid-phase synthesis (detritylation–oxidation cycles).
- Scale synthesis to mmol level (coupling efficiency >99%).
- Purify (HPLC, PAGE, CE) and characterize (LC-MS, UV-Vis, MS) oligos.
- Maintain lab instrumentation, inventory, safety, and SOPs.
- Drive cross-functional method development and QC initiatives.
Qualifications:
- Ph.D. + 2–5 yrs in oligo synthesis and analysis.
- Strong foundation in phosphoramidite chemistry, purification, analytics.
- Bonus: experience with modified or therapeutic oligos, digital PCR/BEAMing.
Why This Role is Rewarding:
As a Synthesis Scientist, you will be part of a dynamic team driving innovation in genomics and diagnostics. We offer a supportive environment, opportunities for growth, and the chance to make a meaningful impact.
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