
▷ Only 24h Left Group Lead-invitro Adme
2 hours ago
Job Title Group Lead - Invitro ADME Job Location Hyderabad About Syngene Syngene is an innovation-led contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply At Syngene safety is at the heart of everything we do personally and professionally Syngene has placed safety at par with business performance with shared responsibility and accountability including following safety guidelines procedures and SOPs in letter and spirit Mandatory expectation for all roles as per Syngene safety guidelines Overall adherence to safe practices and procedures of oneself and the teams aligned Contributing to development of procedures practices and systems that ensures safe operations and compliance to company s integrity quality standards Driving a corporate culture that promotes environment health and safety EHS mindset and operational discipline at the workplace at all times Ensuring safety of self teams and lab plant by adhering to safety protocols and following environment health and safety EHS requirements at all times in the workplace Ensure all assigned mandatory trainings related to data integrity health and safety measures are completed on time by all members of the team including self Compliance to Syngene s quality standards at all times Hold self and their teams accountable for the achievement of safety goals Govern and Review safety metrics from time to time Core Purpose of the Role Lead a high-performing team of scientists in designing executing and interpreting complex in-vitro ADME and transporter studies that directly influence molecule progression decisions Own scientific strategy ensure operational excellence and contribute to cross-functional project leadership in a dynamic drug discovery environment Role Accountabilities Develop and evolve strategic in-vitro ADME and transporter capabilities aligned with current and emerging drug discovery needs Spearhead design and interpretation of advanced cell- and non-cell-based ADME assays including Stability solubility logD logP plasma protein binding and permeability assays Transporter-based uptake and efflux studies using relevant in-vitro models e g Caco-2 MDCK-MDR1 hepatocytes Integration of transporter data with PK profiling to guide compound selection and liability assessment Review and harmonize physicochemical properties with permeability binding and transporter interaction data to drive optimal candidate selection Lead evaluation and implementation of new assay formats for transporter kinetics inhibition and substrate specificity in collaboration with external partners Drive automation initiatives and assess emerging technologies e g high-throughput platforms machine learning models for transporter prediction Ensure robust and validated use of instrumentation such as Sirius T3 for pKa and logP measurement and LC-MS MS for transporter studies Oversee quality scalability and compliance of transporter assays for regulatory and early discovery applications Lead and mentor scientists and associates team size 10-20 foster a culture of ownership accountability and scientific curiosity Set and evaluate KRAs OKRs provide clear career development pathways performance feedback and technical growth opportunities Promote talent retention by recognizing contributions and aligning roles with strengths and growth ambitions Serve as scientific point-of-contact for DMPK-related deliverables including transporter studies in multi-disciplinary discovery programs Collaborate closely with Medicinal Chemistry Assay Biology BA-DMPK Toxicology and other functions to ensure seamless project execution Present strategic insights transporter findings and recommendations in internal and client-facing forums contribute to reports and publications Ensure full adherence to Syngene s policies on data integrity safety ethics and quality systems Lead audit readiness of in-vitro ADME and transporter labs continuously improve SOPs EOPs and training modules Monitor safety metrics and near-miss incidents lead corrective preventive actions with commitment to lab excellence Syngene Values All employees will consistently demonstrate alignment with our core values Excellence Integrity Professionalism Accountabilities as a Syngene Leader Champion effective Environment Occupational Health Safety and Sustainability EHSS practices for the company and oversee compliance with those practices within Biologics business Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities Foster a corporate culture that promotes an environment occupational health safety and sustainability EHSS mindset as well as the highest standards of quality integrity and compliance Put people at the heart of our success by providing clear active leadership defined by the Syngene leadership framework setting high standards of people management career planning and talent retention as a priority Experience A Ph D in pharmaceutical sciences or biological science with 6-10 year s of experience with a track record in drug discovery Ph D or M Pharm in pharmaceutical sciences with fifteen or more years of Industrial experience in DMPK ADME research Educational Qualification A Ph D or Postdoctoral experience in pharmaceutical or biological sciences or M Pharm in any pharmaceutical science Technical functional Skills Advanced knowledge of ADME PK PD Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assays Sound knowledge in troubleshooting assays Skilled in using Microsoft Excel and GraphPad Prism for robust data analysis visualization and interpretation Cross functional team leadership and mentoring Strategic decision making and data interpretation Behavioral Skills Demonstrate ability to be a team player Commitment to deliver the study reports within the agreed timelines Adaptability to changes in the dynamic lab environment Communicate confidently with colleagues and collaborators in the meetings and presentation of study reports and evidence of publications in the PEER reviewed Journals Equal Opportunity Employer It is the policy of Syngene to provide equal employment opportunity EEO to all persons regardless of age color national origin citizenship status physical or mental disability race religion creed gender sex sexual orientation gender identity and or expression genetic information marital status status with regard to public assistance veteran status or any other characteristic protected by applicable legislation or local law In addition Syngene will provide reasonable accommodations for qualified individuals with disabilities
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invitro ADME scientist
5 days ago
Shamirpet mandal, India Syngene International Limited Full time ₹ 12,00,000 - ₹ 36,00,000 per yearJob Title: Invitro ADME ScientistJob Location: HyderabadDepartment: Discovery BiologyAbout SyngeneIncorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and...
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Only 24h Left In Vitro Ba Scientist
4 weeks ago
Shamirpet, Telangana, India Syngene International Full timeJob Title in-vitro Bioanalytical Scientist Job Location Hyderabad About Syngene Syngene is an innovation-led contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply At Syngene safety is at the heart of everything we do personally and professionally Syngene...
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Associate Scientist Only 24h Left
4 weeks ago
Shamirpet, Telangana, India Syngene International Full timeJob description Job title Associate Scientist Job location Hyderabad Job grade 8-I About Syngene Syngene is an innovation-led contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply At Syngene Safety is at the heart of everything we do personally and...
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Only 24h Left: Senior Research Associate
4 weeks ago
Shamirpet, Telangana, India Syngene International Full timeJob description Job title Senior Research Associate Job location Hyderabad Job grade 9-II About Syngene Syngene is an innovation-led contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply At Syngene Safety is at the heart of everything we do personally and...
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In Vitro Ba Scientist
3 weeks ago
Shamirpet, Telangana, India Syngene International Full timeJob Title In-vitro Bioanalytical Scientist Job Location Hyderabad About Syngene Syngene is an innovation-led contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply At Syngene safety is at the heart of everything we do personally and professionally Syngene...
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(Only 24h Left) Medical Coding Analyst
1 week ago
Hyderabad, Telangana, India UnitedHealth Group Full timeOptum is a global organization that delivers care aided by technology to help millions of people live healthier lives The work you do with our team will directly improve health outcomes by connecting people with the care pharmacy benefits data and resources they need to feel their best Here you will find a culture guided by inclusion talented peers ...
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Hyderabad, Telangana, India Apex Group Full timeThe Apex Group was established in Bermuda in 2003 and is now one of the world s largest fund administration and middle office solutions providers Our business is unique in its ability to reach globally service locally and provide cross-jurisdictional services With our clients at the heart of everything we do our hard-working team has successfully...
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Hyderabad, Telangana, India Novartis Full timeSummary This role is accountable for managing and leading a Medical Information delivery team to produce high- quality medical information documents and responses Associate Director Medical Information Group Lead Location - Hyderabad LI Hybrid About the Role This role is accountable for managing and leading a Medical Information delivery team to...
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Only 24h Left! Ios Technical Lead
7 days ago
Hyderabad, Telangana, India OSI Digital Full timeJob Title Associate Technical Lead Experience 6 - 8 Years Location Hyderabad INDIA OSI Digital is looking for a hands-on and technically strong iOS Technical Lead with 6 years of experience in building scalable high-performance mobile applications The ideal candidate will combine deep knowledge of Swift SwiftUI and Apple s ecosystem with...
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▷ Only 24h Left! Quality Auditor
2 weeks ago
Hyderabad, Telangana, India UnitedHealth Group Full timeOptum is a global organization that delivers care aided by technology to help millions of people live healthier lives The work you do with our team will directly improve health outcomes by connecting people with the care pharmacy benefits data and resources they need to feel their best Here you will find a culture guided by diversity and inclusion ...