Invitro Ba Scientist

Job Title in-vitro Bioanalytical Scientist Job Location Bangalore About Syngene Syngene is an innovation-led contract research development and manufacturing organization offering integrated scientific services from early discovery to commercial supply At Syngene safety is at the heart of everything we do personally and professionally Syngene has placed safety at par with business performance with shared responsibility and accountability including following safety guidelines procedures and SOPs in letter and spirit Mandatory expectation for all roles as per Syngene safety guidelines Overall adherence to safe practices and procedures of oneself and the teams aligned Contributing to development of procedures practices and systems that ensures safe operations and compliance to company s integrity quality standards Driving a corporate culture that promotes environment health and safety EHS mindset and operational discipline at the workplace at all times Ensuring safety of self teams and lab plant by adhering to safety protocols and following environment health and safety EHS requirements at all times in the workplace Ensure all assigned mandatory trainings related to data integrity health and safety measures are completed on time by all members of the team including self Compliance to Syngene s quality standards at all times Hold self and their teams accountable for the achievement of safety goals Govern and Review safety metrics from time to time Core Purpose of the Role To participate in sample processing for PK ADME assays and handling of LCMS MS Ability to adapt to the dynamic team environment Processing of different matrices samples of PK studies Optimization of test compounds manually as well as automated on LCMS MS Develop methods with the team lead Independently handling of HPLC for UV based samples analysis Documenting the lab note books online and compound management Syngene Values All employees will consistently demonstrate alignment with our core values Excellence Integrity Professionalism Accountabilities as a Syngene Leader only for Leadership Hires Champion effective Environment Occupational Health Safety and Sustainability EHSS practices for the company and oversee compliance with those practices within Biologics business Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities Foster a corporate culture that promotes an environment occupational health safety and sustainability EHSS mindset as well as the highest standards of quality integrity and compliance Put people at the heart of our success by providing clear active leadership defined by the Syngene leadership framework setting high standards of people management career planning and talent retention as a priority Experience Minimum 3-5 years of experience in handling ADME assays and HPLC and LCMS MS Skills and Capabilities Expertise in column selection mobile phase selection solvent preparations and sample processing techniques such as protein precipitation liquid-liquid extraction and solid phase extraction is mandatory Sample processing of New chemical entities from various in-vitro and in-vivo studies executed in Preclinical discovery by using appropriate extraction methods Should be able to develop and validate LC-MS based qualitative quantitative methods and apply them in routine analysis Should be well versed with internet-based literature search and capable of implementing the Learnings as and when required Candidate is expected to have basic understanding in interpretation of Mass UV Spectra Should ensure preventative maintenance and calibration schedules of HPLC mass spec by coordinating with vendor and support staff General understanding of Drug metabolism and Pharmacokinetics Should be able to deliver scientific presentation in departmental journal club and write official Project reports Education M Pharm in Pharmaceutical sciences Pharmaceutical Analysis who has interest and passion for LC MS related bioanalysis Equal Opportunity Employer It is the policy of Syngene to provide equal employment opportunity EEO to all persons regardless of age color national origin citizenship status physical or mental disability race religion creed gender sex sexual orientation gender identity and or expression genetic information marital status status with regard to public assistance veteran status or any other characteristic protected by applicable legislation or local law In addition Syngene will provide reasonable accommodation for qualified individuals with disabilities