▷ (15h Left) Analytical / Conjugation - Assistant Manager

7 days ago

Dera Bassi Bassi India Panacea Biotec Full time

Job Description

Roles and Responsibility: Analytical /Conjugation

Analytical Characterization

- Development of assays for Protein and Carbohydrate characterization.
- Standardization and optimization of various Biochemical assays.
- Immunochemical methods of analyses such as ELISA, SDS-PAGE, slot blotting and Western blotting.
- Instrumental methods of analyses such as LC-MS, Protein sequencing, HPLC, ELISA reader, AKTA, Spectrophotometer and RT-PCR.
- Knowledge and implementation of different need based chromatographic techniques in lab.
- Analytical method development for physicochemical characterization of Protein and Polysaccharide based vaccines.

Conjugation/DSP Process Development

- Execute chemical conjugation experiments for polysaccharideprotein and other vaccine platforms.
- Support optimization of reaction parameters (e.g., molar ratios, pH, buffers, coupling agents).
- Perform quenching, purification, and yield improvement studies.
- Operate and optimize purification techniques (UF/DF, chromatography, precipitation, filtration).
- Support scale-up studies from bench to pilot level.
- Ensure consistency in product yield, recovery, and purity.

Documentation & Compliance

- Maintain detailed experiment records, data integrity, and lab notebooks.
- Support in preparation of technical reports, SOPs, and batch manufacturing records.
- Ensure compliance of internal quality standards.

Cross-functional Collaboration

- Work closely with upstream, formulation, analytical, and quality teams for seamless project execution.

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