Analytical / Conjugation - Assistant Manager

6 days ago

Dera Bassi, India Panacea Biotec Full time

Roles and Responsibility: Analytical /Conjugation

Analytical Characterization

  • Development of assays for Protein and Carbohydrate characterization.
  • Standardization and optimization of various Biochemical assays.
  • Immunochemical methods of analyses such as ELISA, SDS-PAGE, slot blotting and Western blotting.
  • Instrumental methods of analyses such as LC-MS, Protein sequencing, HPLC, ELISA reader, AKTA, Spectrophotometer and RT-PCR.
  • Knowledge and implementation of different need based chromatographic techniques in lab.
  • Analytical method development for physicochemical characterization of Protein and Polysaccharide based vaccines.

Conjugation/DSP Process Development

  • Execute chemical conjugation experiments for polysaccharide–protein and other vaccine platforms.
  • Support optimization of reaction parameters (e.g., molar ratios, pH, buffers, coupling agents).
  • Perform quenching, purification, and yield improvement studies.
  • Operate and optimize purification techniques (UF/DF, chromatography, precipitation, filtration).
  • Support scale-up studies from bench to pilot level.
  • Ensure consistency in product yield, recovery, and purity.

Documentation & Compliance

  • Maintain detailed experiment records, data integrity, and lab notebooks.
  • Support in preparation of technical reports, SOPs, and batch manufacturing records.
  • Ensure compliance of internal quality standards.

Cross-functional Collaboration

  • Work closely with upstream, formulation, analytical, and quality teams for seamless project execution.

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