Senior Research Associate

1 week ago


Shamirpet Telangana, India Syngene International Full time

Job Overview The UPLC-MS Analyst is responsible for conducting ultra-performance liquid chromatography and mass spectrometry analyses on a wide variety of samples including pharmaceutical environmental and biological samples The role involves sample preparation method development and analysis using UPLC-MS techniques to identify quantify and characterize compounds The analyst works closely with research and development teams to support studies ensuring accurate and timely results Key Responsibilities Operate and maintain UPLC-MS LCMS systems for the separation identification and quantification of compounds in various sample matrices Perform routine analyses and troubleshoot issues with instrumentation Develop and validate UPLC-MS LCMS methods tailored to specific sample types and research goals optimizing separation conditions mobile phases and mass detection parameters Prepare samples for UPLC-MS LCMS analysis including dilutions extractions filtrations and derivatization ensuring accurate and reliable results Process and interpret complex data from UPLC-MS LCMS runs including peak identification quantitation and mass spectral analysis Provide comprehensive reports and summaries of results Perform routine maintenance calibration and troubleshooting of UPLC-MS LCMS instruments Schedule service and repairs when necessary to ensure continuous reliable operation Ensure all analyses meet the required standards for accuracy and precision Follow Good Laboratory Practices GLP Work with chemists to meet analytical needs Provide input on experiment design sample handling and method optimization Adhere to laboratory safety protocols and maintain records to ensure compliance with regulatory and internal standards Maintain accurate and detailed records of all experiments methods and results Follow all laboratory safety protocols and ensure compliance with regulatory guidelines for handling chemicals and hazardous materials Maintain accurate records for regulatory and quality control audits Required Hands of experience in Prep HPLC LCMS and NMR to evaluate the compounds



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