Research Scientist

3 weeks ago

Bengaluru, Karnataka, India Foundation for Neglected Disease Research Full time
Job Description

Company Overview: Foundation for Neglected Disease Research (FNDR) is a not-for-profit biotech R&D organization dedicated to discovering and developing novel therapeutics, diagnostics, and devices for diseases with a high socio-economic impact. Since its inception in 2014, FNDR has generated a portfolio of therapeutics in tuberculosis, nontuberculous mycobacteria, malaria, dengue, leishmania, serious bacterial infections, fungal infections, COVID-19 and RSV, spanning over early-stage discovery to late-stage clinical trials. FNDR's R&D Centre, which includes state-of-the-art BSL2 and BSL3 laboratories for both in vitro and in vivo research, is in Bengaluru, India. For more information, please visit https://www.fndr.in/.

Minimum Qualification:

- M.Sc. in Organic Chemistry, Medicinal Chemistry, or a closely related field
- PhD in organic chemistry / medicinal chemistry
- Postdoc in organic chemistry / Medicinal chemistry (Optional)
- 0-4 years of hands-on experience in working on bench, preferably in an industry

Responsibilities:

- Design and execute synthetic routes to prepare small molecules for drug discovery programmes
- Track SAR and optimizing potency, selectivity, and properties of small molecules for research programs
- Perform purification and structural characterization of compounds
- Troubleshoot synthetic problems and optimize reaction conditions
- Providing mentorship and guidance to junior colleagues
- Maintain accurate lab records and contribute to technical reports
- Collaborate with analytical teams as needed
- Providing input on intellectual property activities

Technical and Soft Skills:

- Skilled in multistep organic synthesis, reaction optimization, and compound isolation
- Proficient in chromatography (TLC, column, flash), spectroscopic analysis (NMR, LC-MS, HPLC), and purification techniques (recrystallization, precipitation, others)
- High level of creativity and productivity with strong synthetic chemistry problem solving skills
- Demonstrated excellence in organic synthesis, conversant with the current literature
- Effective oral and scientific/technical writing communication skills
- Ability to work independently and collaboratively within a team
- Commitment to lab safety and adherence to safety protocols
- Familiarity with reaction databases (e.g., Reaxys, SciFinder)
- Proficiency using MS Office applications is required

CTC Range: Commensurate to experience and negotiable.

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