BBRC - Research Investigator - Process Research & Development

2 months ago

Bengaluru, India Syngene International Limited Full time

JOB DESCRIPTION


Designation: Research Investigator (7-I) / Senior Research Investigator (7-II)

Job Location: Bangalore

Department: Process Research & Development


About Syngene,

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.


Job Purpose (1-2 Lines)

Looking for a synthetic organic/physical chemist (PhD Organic/physical Chemistry) who will be able to address synthetic challenges, investigate mechanistic aspects and support scale-up activities in the process research and development group. Experience in using analytical PAT tools for mechanistic driven optimization


Key Responsibilities: (Maximum 5-8 Points)

The candidate should be willing to work in the lab as an individual contributor with responsibilities towards development of safe and robust chemical processes for the preparation of intermediates/API in support of drug development activities.


Development work includes:

• Investigate mechanistic aspects using PAT tools

• Willing to carry out reactions at bench to support R&D activities

• Fit for purpose, accelerating API delivery

• Mechanistic driven optimization and collaborate with other stakeholders for rapid delivery of API’s.

• Providing insights and innovative solutions to project team members in order to address process related challenges/process safety, understand key impurities formation during reaction and isolation stages – propose relevant mechanisms.

• Candidate should communicate effectively with his own team members as well as with multiple teams like process engineering, process safety, analytical etc.

• Communicating & documenting development on the project through regular updates with concerned stakeholders.


Educational Qualification:

PhD in organic/physical chemistry with postdoctoral experience (1-3 year) candidate from reputed institute/university (India/abroad).


Technical/functional Skills: (Maximum 4-6 Points)


Essential:

• Good understanding of organic chemistry fundamentals and reaction mechanisms.

• Strong track record of publications in reputed international journals.

• Coordination with multi-disciplinary teams of process R and D, analytical team, pilot plant, process safety, quality control and quality assurance personnel.


Preferable:

• Previous experience in Pharmaceutical Process R&D.

• Understanding of analytical data generated from NMR, HPLC, GC, IR, Raman, etc.

• Experience in using analytical PAT tools like React IR & Raman will be an added advantage

• Willingness to work with Catalysis & Biocatalysis teams, and learn screening techniques to support R&D optimization


Experience:

1-3 yrs


Behavioral Skills:

• Should be a good team player capable of working well in cross functional teams.

• Should be self-motivated, creative and independent.


Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

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