R & D Department - Research Associate/ Research Executive

2 days ago

Navsari, India Gufic Group Full time

Role & responsibilities

Job Description/Responsibility for 5-7 Years Experience candidate (Designation: Sr. Research Executive-SRE)

  1. Candidate must have throughout experience in Peptide process development
  2. Must be familiar with the designing of peptide drug substances route of synthesis
  3. Sound knowledge about the capping/cyclization of peptide chain
  4. Knowledge about protection and Deprotection of amino acids
  5. Knowledge about global deprotection of peptide form Peptidyl resin
  6. Must be familiar about the isolation of crude peptide
  7. Knowledge about the critical process parameters of solid phase Peptide synthesis
  8. Basic knowledge about purification techniques for crude Peptide
  9. 9.Able to handle 100 mm DAC as on required
  10. Must be familiar with peptide synthesis process scale up

Job Description/Responsibility for 2-3 Years Experience candidate (Designation: Sr. Research Associate-SRA or Research Executive-RE)

  1. Candidate must have experience in Peptide process development
  2. Able to perform experiment as suggested by team leader
  3. Knowledge about protection and Deprotection of amino acids
  4. Knowledge about global deprotection of peptide form Peptidyl resin
  5. Must be familiar about the isolation of crude peptide
  6. Knowledge about the critical process parameters of solid phase Peptide synthesis
  7. Basic knowledge about purification techniques for crude Peptide

Job Description/Responsibility for– 2-4 Years Experience candidate (Designation: Sr. Research Associate-SRA or Research Executive-RE)

  1. Responsible for Column packing and un-packing activity for purification trials
  2. Responsible for Column Performance Test (CPT)
  3. Peptide & API Purification method development on preparative HPLC
  4. Perform downstream-Purification of Crude Peptide on 100 mm DAC
  5. Define pooling strategy/control strategy for Purification method
  6. Preform salt exchange activity on 100 mm DAC
  7. Generate report for Design of Experiment (DoE) for Purification
  8. Co-work for solid phase up-stream synthesis
  9. Perform and optimization of global deprotection of Peptidyl resin

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