AGM - Mammalian Upstream Lab

4 weeks ago

Mumbai, Maharashtra, India USV PRIVATE LIMITED Full time
USV Biologics is hiring
We are a 63 year old healthcare company recognized for our leadership in the oral antidiabetic & cardiovascular disease therapeutic segments in India. Our Biologics Program comprises molecular biology, upstream and downstream, analytical and bioanalytical teams and biologics regulatory affairs operating out of Govandi, Mumbai. USV's first commercialized biosimilar, Pegfilgrastim (GRASUSTEK) has received marketing authorization in the EU and some other countries and has been marketed for the past 5 years.
USV Biologics is expanding into mammalian biosimilars and is building a team for the Mammalian program in R&D.
We are hiring AGM - Mammalian Upstream Lab (BRL) , who will play a pivotal role in setting up the lab, and further work on target molecules to advance them to the next stage. This position will be based at our Corporate Office and R&D Center at Govandi ( East), Mumbai.
The suitable candidate must have Knowledge of biosimilar upstream process development in mammalian
(CHO expression system)
Should have experience :
In process development including media feed screening and physical parameters optimization
In Handling of CHO based cultures at shake flask level, ambr15 and ambr250 scales
Handling in 5L and 50L with Multiple and Single use disposable upstream equipment
Scale up process, technology transfer (2-4 projects) 7 & troubleshooting of scaleup related activities
Process characterization
Working under quality management systems
Setting up a mammalian upstream lab
Preparation of different reports related to upstream process development
Plan and coordinate activities with cross functional teams (CFTs) such as clone development, downstream, analytical and manufacturing teams.
Lead a team of scientists in upstream team & able to mentor team to solve challenging problems
Qualification & other details:
Msc with 13-16 years of experience or PhD with 8-12 years of experience in upstream lab
(Mandatory experience in Mabs project: project development and scale up)
Reporting : 3-4 (Team will be recruited post Lead joins)
Position reports to : General Manager

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