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Structural Biologist
2 months ago
Job Location: Bangalore
About Syngene: Syngene ( is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit
Mandatory expectation for all roles as per Syngene safety guidelines:
Overall adherence to safe practices and procedures of oneself and the teams aligned
Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
Compliance to Syngene’ s quality standards at all times
Hold self and their teams accountable for the achievement of safety goals
Govern and Review safety metrics from time to time
Core Purpose of the Role :
Have strong working knowledge of protein sciences, drug discovery, project leadership and people management.
Experience in protein crystallization, co-crystallization with small molecule ligands/inhibitors, X-ray diffraction, data collection and structural refinement. Experience in Cryo-EM based structure solutions is desirable.
Sound knowledge of Gene-2-Protein workflow across multiple platforms (Bacterial, Yeast, Insect and Mammalian).
Sound knowledge of protein analytics (HPLC, LC-MS) and assays measuring biomolecular interactions (SPR, BLI, nanoDSF)
Work independently on designing experiments, analyzing data and presenting to client. Out of the box thinking to solve complex biological problems
Demonstrate experience and maturity handling high-performing teams in a matrix environment while leading a team of M.Sc level scientists directly reporting in.
Sufficient skills for globally competitive scientific proposal writing to gain new business
Handle technical, operational, and managerial workflows and seamlessly move between these.
Role Accountabilities:
Manage optimum utilization of resources and people to ensure timely delivery of project deliverables, ensuring operational excellence.
Participate in proposal writing on new client projects, and new capability developments
Proactively communicate with client to manage client expectations, clarifying queries, recommending ideas and interpreting data.
Adequate behavioral skills & ability to build cross-functional relationships ensuring the delivery of projects on-time with quality efficiency.
Leadership Capabilities:
Should be client facing and responsible for managing a team
Accountable for the scientific data and reports
Responsible for project delivery
Specific requirements for this role:
Experience: 8-12 years (post PhD)
Education: PhD
Skills and Capabilities:
Expert knowledge of advanced macromolecular structural biology,
Working knowledge of diverse protein sciences platforms (molecular biology, upstream and downstream processes) as well as biophysical assays.
Track record of strong organizational, communication and problem-solving abilities; capable of absorbing different types of information; work independently; and thrive on a highly collaborative and fast-moving environment.
Behavioral Skills:
Good work ethics.
Good interpersonal skills, and the ability to work effectively in a team environment.
Ability to work with co‐workers professionally.
General ability to thrive in a growing infrastructure and culture and also think out of box approach when troubleshooting and problem solving.
Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
