Principal Investigator
1 week ago
JOB DESCRIPTION
Designation: Principal Investigator
Job Location: Bangalore
Department: CDAS
About Syngene
Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.
Job Purpose (1-2 Lines)
• Lead activities on assigned CDAS projects, report progress to BMS counterparts through regular updates. Pro-actively find solutions to synthesis and process related challenges.
• Enabling rapid optimization of reactions, through rapid screening of reaction conditions, enabling implementation in kilo lab and (or) pilot plant.
Key Responsibilities: (Maximum 5-8 Points)
1. Go through the technical package received from BMS and understand the requirements.
2. In discussion with relevant stakeholders, work out a clear workplan and implement the same.
3. Communicate/discuss project related requirements. Discuss results with relevant stakeholders.
4. Get relevant BMS project leader’s/lead scientist’s feedback and work on resolution of the concerns pro-actively.
5. Record the observations as per BMS guidelines using ELN.
6. Ability to lead a group of senior chemists.
7. Mentor and train scientists on reaction screening as required. Delegate work as appropriate.
8. Prepare periodic updates as required. Present results in review meetings and work on solutions proposed in meetings as appropriate.
9. Ensure lab safety guidelines and always followed in lab. Report and escalate non-compliance as appropriate.
Educational Qualification:
1. Ph.D with 1-3 years of Post-Doc experience
2. 2-3 years of relevant industrial experience
3. Not less than 5 publications in relevant journals.
Technical/functional Skills: (Maximum 4-6 Points)
1. Carrying out air sensitive organic reactions, safely, on mg to g scales.
2. Operating glove box and related equipment without assistance.
3. Thorough understanding of basic organic reactions and synthetic methodology.
4. Presentation skills (making slides using ppt or similar software).
5. Good communication skills.
Experience:
2 to 3 years
Coordination with multi-disciplinary teams of process R & D, pilot plant, process safety, quality control and quality assurance personnel.
Preferable:
1. Previous experience in Pharmaceutical Process R&D (2 to 3 years).
2. Understanding of analytical data generated from NMR, HPLC, GC etc.
3. Good understanding of cGMP
Behavioral Skills:
1. Must be a good team player.
2. Good communication skills.
3. Must be able to demonstrate the biopharma behaviours.
Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
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