Head Pharmacology

Position Purpose Strategic Responsibilities Operational Responsibilities Build and lead a discovery biology group with capabilities to execute integrated drug discovery projects, including discovery in vitro pharmacology, biochemistry, immunology, protein sciences, structural biology, in vivo, translational and cell biology. Responsible for the target identification, discovery, and pre-clinical development leading to new clinical candidates. Actively provide creative and innovative leadership for discovery biology enabling project progress from biological hypotheses into transformative medicines. Enable the creation of various target related in vitro assays and provide necessary support for the development of in vivo models and pharmacology experiments in support of program objectives. Expand the company's external network through identification/recommendation of thought leaders and advisors to the CSO and establish deep domain area expertise in program areas such as immunology/inflammation, immuno-oncology, autoimmunity and inflammation. Construct and manage spending budgets and project resourcing. Responsible for identifying and building lab infrastructure to support a high-throughput discovery engine equipped with digital data processing and communication (eLNB and LIMs). Keep up-to-date with the latest therapeutic modalities, scientific advances, technologies, and trends in and development to deliver the next generation of therapies. Explore academia collaborations to enhance innovative approaches for drug screening. Work closely with BD and Sales team to ensure “win outcomes” for proposals/RFP for FTE and FFS projects submissions. Ensure seamless integration with project management team and scientific teams to achieve excellence in delivering project related milestones with high data credibility with an “ON TIME-EVERYTIME” and ALCOA+ Principles for Data Integrity in Life Sciences. Ensure data integrity, following all the SOPs and guidelines as per ALCHOA principles. Ensure safety regulations and implemented in accordance with company’s safety regulations to achieve “zero tolerance” policy. Financial Responsibilities Preparation of annual/five year CAPEX and FTE utilisation/projections keeping in mind the company and departmental objectives. Ensure Discovery Biology teams adhere to budget (CAPEX/REVEX) as required by the project. Determine appropriate FTE/FFS rates for client proposals after through due diligence. Work closely with BD and Sales teams and oversee scientific proposal preparation, RFP preparation and submissions in alignment with company policies. Work closely with BD and Project management teams to track milestones, timelines and revenues with focus on proposal cost and pricing (to maximise P&L). People Responsibilities Build and lead a strong team of directors, scientists, and RAs in in vitro, in vivo, ADME and translational sciences, to achieve company milestones. Enable the Discovery Biology team to collaborate closely with, chemistry, and DMPK groups to drive discovery and lead optimization and pre-clinical characterization of multiple projects across discovery programs. Support and ensure effective interaction and communication between Biology, Chemistry, and DMPK teams, in alignment client requirements and leadership teams. Interact with all stakeholders to enable timely and accurate communication on project progress towards meeting project goals and timelines. Education Qualification A proven scientific leader with a Ph.D. in Immunology/Biology/Biochemistry/Cell Biology 20+ years of biotechnology and pharmaceutical drug discovery R&D experience. Work Experience Demonstrated strong leadership and team management skills with experience in building and retaining high-performing scientific teams, with an ability to work within a matrixed structure across the drug discovery continuum. Therapeutic domain expertise in immunology, oncology, inflammation and autoimmunity and rare diseases with extensive experience in CRO management in these therapeutic areas. Industry to be Hired from Pharma/CRO/CDMO Functional Competencies Teamwork & Collaboration Should have a proven track record of successfully advancing therapeutic programs from early discovery through to CCN Should possess outstanding interpersonal, collaborative and operational skills with experience guiding and motivating successful teams and building leaders for the organisation aligned with company goals and vision A demonstrated ability to think logically and critically and to develop innovative approaches to answering complex biological questions Passion for identifying and implementing latest technologies and modalities driving drug discovery in the pharma industry Interaction Complexity and Team Work Interaction Complexity & Team work Interaction Frequency Purpose of Interaction Internal : Senior management and team As and when required Operational insight, financials, project status.